The treatment of chronic osteomyelitis with clindamycin

Clindamycin was given orally over prolonged periods to 12 patients with chronic osteomyelitis. It was well tolerated with only minor side effects and no major toxicity. Clinical and bacteriological cure occurred in five patients and improvement was noted in another five. It appears less effective th...

Full description

Saved in:
Bibliographic Details
Published in:Canadian Medical Association journal 1973-07, Vol.109 (2), p.105-107
Main Authors: Pontifex, A H, McNaught, D R
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Child
Chronic Disease
Clindamycin - administration & dosage
Clindamycin - adverse effects
Clindamycin - pharmacology
Clindamycin - therapeutic use
Clinical Trials as Topic
Humans
Lincomycin - therapeutic use
Microbial Sensitivity Tests
Micrococcus - drug effects
Micrococcus - isolation & purification
Middle Aged
Original
Osteomyelitis - drug therapy
Osteomyelitis - microbiology
Staphylococcus - drug effects
Staphylococcus - isolation & purification
Time Factors
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Clindamycin was given orally over prolonged periods to 12 patients with chronic osteomyelitis. It was well tolerated with only minor side effects and no major toxicity. Clinical and bacteriological cure occurred in five patients and improvement was noted in another five. It appears less effective than either lincomycin or cloxacillin but, because of the complex nature of both the disease and its treatment, strict comparisons are very difficult.
ISSN:0008-4409