Role of nephrectomy in hypertension with renal artery occlusion

Nephrectomy was performed in 12 patients with complete renal artery occlusion and hypertension refractory to intensive medical therapy. Renal vein renin was assayed preoperatively in 10 of the 12, and in 8 the ratio was at least 1.5:1, strongly suggesting renal artery occlusion on the side with the...

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Bibliographic Details
Published in:Canadian Medical Association journal 1976-01, Vol.114 (2), p.132-134
Main Authors: Bourdeau, G. V, Morrs, D. E, Jindal, S. L
Format: Article
Language:English
Subjects:
Aged
Cardiovascular Diseases - etiology
Follow-Up Studies
Humans
Hypertension, Renal - complications
Hypertension, Renal - pathology
Hypertension, Renal - surgery
Ischemia - blood
Kidney - pathology
Middle Aged
Nephrectomy
Renal Artery Obstruction - blood
Renal Artery Obstruction - diagnostic imaging
Renal Artery Obstruction - surgery
Renal Veins
Renin - blood
Urography
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Summary:Nephrectomy was performed in 12 patients with complete renal artery occlusion and hypertension refractory to intensive medical therapy. Renal vein renin was assayed preoperatively in 10 of the 12, and in 8 the ratio was at least 1.5:1, strongly suggesting renal artery occlusion on the side with the higher concentration of renin in venous blood. In two patients peripheral plasma renin activity was very high before operation, then decreased greatly afterwards. Three patients were considered cured and eight improved (overall improvement rate, 92%). The results were predicted by the renin ratio.
ISSN:0008-4409