Immunoreactive inhibin-like material in serum and gastric juice of patients with benign and malignant diseases of the stomach

Immunoreactive inhibin-like material (ILM) was measured by radioimmunoassay (RIA) in serum and gastric juice samples of 23 fasting normal men, 27 men with chronic superficial gastritis (CSG), and 21 men with carcinoma of stomach (5 for gastric analysis). Serum ILM levels in carcinoma of stomach pati...

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Bibliographic Details
Published in:British journal of cancer 1985-06, Vol.51 (6), p.877-882
Main Authors: Shanbhag, S A, Sheth, A R, Nanivadekar, S A, Sheth, N A
Format: Article
Language:English
Subjects:
Adult
Biomedical and Life Sciences
Biomedicine
Cancer Research
Cross Reactions
Drug Resistance
Epidemiology
Gastric Juice - analysis
Gastrointestinal Hormones - analysis
Humans
Hydrogen-Ion Concentration
Inhibins - analysis
Inhibins - blood
Male
Middle Aged
Molecular Medicine
Oncology
original-article
Radioimmunoassay
Stomach Diseases - blood
Stomach Diseases - metabolism
Stomach Neoplasms - analysis
Stomach Neoplasms - blood
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Summary:Immunoreactive inhibin-like material (ILM) was measured by radioimmunoassay (RIA) in serum and gastric juice samples of 23 fasting normal men, 27 men with chronic superficial gastritis (CSG), and 21 men with carcinoma of stomach (5 for gastric analysis). Serum ILM levels in carcinoma of stomach patients (367 +/- 55.5 ng ml-1) were significantly higher than in normal men (15.4 +/- 2.6 ng ml-1; P less than 0.01) and in patients with CSG (109.8 +/- 17.7 ng ml-1; P less than 0.05). Sixty two per cent and 86% of patients with carcinoma of stomach showed elevated ILM levels which were higher than the highest noted in patients with CSG and normal men respectively.
ISSN:0007-0920
1532-1827
DOI:10.1038/bjc.1985.133