Abortion before first livebirth and risk of breast cancer

The present study examined the association between abortion prior to a first livebirth and breast cancer risk among a cohort of 3,315 women who had been delivered of liveborn children between 1946 and 1965 in a group of private gynaecology practices in Connecticut and followed through 1980 for the i...

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Bibliographic Details
Published in:British journal of cancer 1986-02, Vol.53 (2), p.281-284
Main Authors: Hadjimichael, O C, Boyle, C A, Meigs, J W
Format: Article
Language:English
Subjects:
Abortion, Spontaneous - complications
Adult
Age Factors
Applied sciences
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Breast Neoplasms - etiology
Cancer Research
Disease Susceptibility
Drug Resistance
Epidemiology
Exact sciences and technology
Female
Gynecology. Andrology. Obstetrics
Humans
Mammary gland diseases
Medical sciences
Menarche
Middle Aged
Molecular Medicine
Oncology
original-article
Other techniques and industries
Pregnancy
Risk
Tumors
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Summary:The present study examined the association between abortion prior to a first livebirth and breast cancer risk among a cohort of 3,315 women who had been delivered of liveborn children between 1946 and 1965 in a group of private gynaecology practices in Connecticut and followed through 1980 for the incidence of cancer. Among women with one livebirth at the time of cohort identification, a spontaneous abortion before this livebirth was associated with a 3.5-fold increase in the risk of breast cancer. The elevation in risk was independent of some of the major risk factors of breast cancer and became more pronounced as the number of years since the abortion increased.
ISSN:0007-0920
1532-1827
DOI:10.1038/bjc.1986.46