Malignancy grading in squamous carcinoma of uterine cervix treated by surgery

Some morphological patterns (histological type, vascular invasion, depth of invasion, lymphocytic infiltrate, mode of spread, necrosis) in 125 cases of squamous cervical carcinoma treated by surgery were analysed and graded in order to identify a histoprognostic score. Clinical data on F.I.G.O. stag...

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Bibliographic Details
Published in:British journal of cancer 1980-03, Vol.41 (3), p.415-421
Main Authors: Pagnini, C Arslan, Della Palma, P, De Laurentiis, G
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Biomedical and Life Sciences
Biomedicine
Cancer Research
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Drug Resistance
Epidemiology
Female
Humans
Menopause
Middle Aged
Molecular Medicine
Neoplasm Invasiveness
Oncology
original-article
Prognosis
Retrospective Studies
Uterine Cervical Neoplasms - mortality
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - surgery
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Summary:Some morphological patterns (histological type, vascular invasion, depth of invasion, lymphocytic infiltrate, mode of spread, necrosis) in 125 cases of squamous cervical carcinoma treated by surgery were analysed and graded in order to identify a histoprognostic score. Clinical data on F.I.G.O. stage, modality of surgical treatment, age, hormonal state (pre- or post-menopause) and 5-year survival were known for each patient. Two groups (low and high malignancy) were disclosed, and the difference of survival rate between the 2 was highly significant (P less than 0.001).
ISSN:0007-0920
1532-1827
DOI:10.1038/bjc.1980.65