Randomised controlled trial of combined paracetamol and ibuprofen for fever

A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.

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Bibliographic Details
Published in:Archives of disease in childhood 2006-05, Vol.91 (5), p.414-416
Main Authors: Erlewyn-Lajeunesse, M D S, Coppens, K, Hunt, L P, Chinnick, P J, Davies, P, Higginson, I M, Benger, J R
Format: Article
Language:English
Subjects:
Acetaminophen
Acetaminophen - therapeutic use
Analgesics
Analgesics, Non-Narcotic - therapeutic use
Anticoagulants
Biological and medical sciences
Body temperature
Child
Child, Preschool
Childhood fever
Children & youth
Climate
Combination drug therapy
Departments
Drug therapy
Drug Therapy, Combination
Emergencies
Emergency medical care
Female
fever
Fever - drug therapy
Fever in children
Flow Charts
General aspects
Humans
Ibuprofen
Ibuprofen - therapeutic use
Infant
Male
Measurement
Medical sciences
Miscellaneous
Nonsteroidal anti-inflammatory drugs
Outcome Measures
preschool
Prevention and actions
Public health. Hygiene
Public health. Hygiene-occupational medicine
Sample Size
Short Report
Temperature
Time Factors
Treatment Outcome
Urban Areas
Citations: Items that cite this one
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Description
Summary:A randomised open label study of the combined use of paracetamol and ibuprofen to rapidly reduce fever is reported. The advantage of using both medications is less than half a degree centigrade in the first hour, and insufficient to warrant routine use.
ISSN:0003-9888
1468-2044
DOI:10.1136/adc.2005.087874