Vaccination against rubella of susceptible schoolgirls in Reading

This study of 724 13-year-old schoolgirls in the County Borough of Reading showed that approximately 25% were susceptible to rubella. 96·1% of the 129 seronegative girls and significant numbers of girls with low rubella HAI antibody titres responded to subcutaneous vaccination with Wistar RA. 27/3 r...

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Bibliographic Details
Published in:Epidemiology and infection 1971-12, Vol.69 (4), p.579-586
Main Authors: Rowlands, D. F., Freestone, D. S.
Format: Article
Language:English
Subjects:
Adolescent
Antibodies
Boroughs
Children
Drug Eruptions
England
Exanthema
Female
Headache - etiology
Humans
Injections, Subcutaneous
Lymphatic Diseases - etiology
Pain
Pharyngitis
Rubella
Rubella - immunology
Rubella - prevention & control
Rubella vaccines
Transponders
Vaccination
Vaccination - adverse effects
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Summary:This study of 724 13-year-old schoolgirls in the County Borough of Reading showed that approximately 25% were susceptible to rubella. 96·1% of the 129 seronegative girls and significant numbers of girls with low rubella HAI antibody titres responded to subcutaneous vaccination with Wistar RA. 27/3 rubella vaccine. The incidence of most reactions after vaccination was similar in those who responded to vaccine and those who were initially immune but did not develop rising antibody titres, but rash, lymphadenopathy and headache occurred significantly more frequently in the susceptible group.
ISSN:0950-2688
0022-1724
1469-4409
DOI:10.1017/S0022172400021859