Adult Niemann-Pick disease type C mimicking features of multiple sclerosis

Because control sonography disclosed persistent splenomegaly, we considered the diagnosis of Niemann-Pick disease type C or Gaucher disease. [...]oligoclonal bands in our patient may also represent an immunological response to cerebral damage caused by Niemann-Pick disease type C. In our patient, Ni...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1997-10, Vol.63 (4), p.552-553
Main Authors: GRAU, ARMIN J, BRANDT, TOBIAS, WEISBROD, MATTHIAS, NIETHAMMER, RAINER, FORSTING, MICHAEL, CANTZ, MICHAEL, VANIER, MARIE T, HARZER, KLAUS
Format: Article
Language:English
Subjects:
Adult
Ataxia
Biological and medical sciences
Cholesterol
Dementia
Diagnosis, Differential
Errors of metabolism
Female
Humans
Letters to the Editor
Lipids (lysosomal enzyme disorders, storage diseases)
Magnetic Resonance Imaging
Medical sciences
Metabolic diseases
Multiple sclerosis
Multiple Sclerosis - pathology
Niemann-Pick Diseases - pathology
Psychosis
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Summary:Because control sonography disclosed persistent splenomegaly, we considered the diagnosis of Niemann-Pick disease type C or Gaucher disease. [...]oligoclonal bands in our patient may also represent an immunological response to cerebral damage caused by Niemann-Pick disease type C. In our patient, Niemann-Pick disease type C mimicked features of multiple sclerosis. [...]in patients with suspected multiple sclerosis in whom dementia or psychosis are the leading symptoms, Niemann-Pick disease type C should be considered as differential diagnosis.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.63.4.552