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Increased Melatonin and Delayed Offset in Menopausal Depression: Role of Years Past Menopause, Follicle-Stimulating Hormone, Sleep End Time, and Body Mass Index

Context: The constellation of endocrine patterns accompanying menopausal depression remains incompletely characterized. Objective: Our objective was to test the hypothesis that the amplitude or phase (timing) of melatonin circadian rhythms differs in menopausal depressed patients (DP) vs. normal con...

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Bibliographic Details
Published in:The journal of clinical endocrinology and metabolism 2008-01, Vol.93 (1), p.54-60
Main Authors: Parry, Barbara L., Meliska, Charles J., Sorenson, Diane L., López, Ana M., Martínez, Luis F., Nowakowski, Sara, Hauger, Richard L., Elliott, Jeffrey A.
Format: Article
Language:English
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Summary:Context: The constellation of endocrine patterns accompanying menopausal depression remains incompletely characterized. Objective: Our objective was to test the hypothesis that the amplitude or phase (timing) of melatonin circadian rhythms differs in menopausal depressed patients (DP) vs. normal controls women (NC). Design: We measured plasma melatonin every 30 min from 1800–1000 h in dim light (
ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2006-2853