Decline in Sulfadoxine-Pyrimethamine-Resistant Alleles after Change in Drug Policy in the Amazon Region of Peru

• Published in: Antimicrobial Agents and Chemotherapy 2008-02, Vol.52 (2), p.739-741
• Main Authors: Zhou, Zhiyong, Griffing, Sean M, de Oliveira, Alexandre Macedo, McCollum, Andrea M, Quezada, Wilmer Marquino, Arrospide, Nancy, Escalante, Ananias A, Udhayakumar, Venkatachalam
• Format: Article
• Language: English
• Subjects: Alleles; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimalarials; Antimalarials - pharmacology; Antimalarials - therapeutic use; Biological and medical sciences; Dihydropteroate Synthase - genetics; Drug Combinations; Drug Resistance; Drug Resistance - genetics; Health Policy; Humans; Malaria, Falciparum; Malaria, Falciparum - drug therapy; Malaria, Falciparum - epidemiology; Mechanisms of Resistance; Medical sciences; Mutation; Peru; Pharmacology. Drug treatments; Plasmodium falciparum; Plasmodium falciparum - drug effects; Plasmodium falciparum - enzymology; Plasmodium falciparum - genetics; Pyrimethamine; Pyrimethamine - pharmacology; Pyrimethamine - therapeutic use; Sulfadoxine; Sulfadoxine - pharmacology; Sulfadoxine - therapeutic use; Tetrahydrofolate Dehydrogenase - genetics
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.00975-07

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