Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq

• Published in: Journal of Zhejiang University. B. Science 2008-02, Vol.9 (2), p.154-159
• Main Authors: Firas, A Al-Bayati, Hassan, F Al-Mola
• Format: Article
• Language: English
• Subjects: Anti-Bacterial Agents - pharmacology; Anti-Infective Agents; Antifungal activity; Antifungal Agents - pharmacology; Antimicrobial agents; Bacillus cereus; Bacteria; Biomedical and Life Sciences; Biomedicine; Biotechnology; Chemistry, Pharmaceutical - methods; Gram-positive bacteria; Humans; Iraq; Medicine, Traditional; Microbial Sensitivity Tests; Microbiology; Plant Extracts - metabolism; Plants, Medicinal; Tribulus - metabolism; Urinary Tract Infections - drug therapy; 伊拉克; 尿路感染; 抗微生物活性; 植物药
• ISSN: 1673-1581; 1862-1783
• DOI: 10.1631/jzus.B0720251

Antimicrobial activity of organic and aqueous extracts from fruits, leaves and roots of Tribulus terrestris L., an Iraqi medicinal plant used as urinary anti-infective in folk medicine, was examined against I l species of pathogenic and non-pathogenic microorganisms： Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Corynebacterium diphtheriae, Escherichia coli, Proteus vulgaris, Serratia marcescens, Salmonella typhimurium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Candida albicans using microdilution method in 96 multiwell microtiter plates. All the extracts from the different parts of the plant showed antimicrobial activity against most tested microorganisms. The most active extract against both Gram-negative and Gram-positive bacteria was ethanol extract from the fruits with a minimal inhibitory concentration （MIC） value of 0.15 mg/ml against B. subtilis, B. cereus, P. vulgaris and C. diphtheriae. In addition, the same extract from the same plant part demonstrated the strongest antifungal activity against C. albicans with an MIC value of 0.15 mg/ml.