Contrast-enhanced versus non-enhanced three-dimensional echocardiography of left ventricular volumes

Background In three-dimensional echocardiography (3DE), individual endocardial trabeculae are not clearly visible necessitating left ventricular (LV) volumes to be measured by tracing the innermost endocardial contour. Ultrasound contrast agents aim to improve endocardial definition, but may delinea...

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Bibliographic Details
Published in:Netherlands heart journal 2008-02, Vol.16 (2), p.47-52
Main Authors: van der Heide, J. A., Mannaerts, H. F. J., Yang, L., Sieswerda, G. T., Visser, C. A., Kamp, O.
Format: Article
Language:English
Subjects:
Cardiology
Medical Education
Medicine
Medicine & Public Health
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Summary:Background In three-dimensional echocardiography (3DE), individual endocardial trabeculae are not clearly visible necessitating left ventricular (LV) volumes to be measured by tracing the innermost endocardial contour. Ultrasound contrast agents aim to improve endocardial definition, but may delineate the outermost endocardial contour by filling up intertrabecular space. Although measurement reproducibility may benefit, there may be a significant influence on absolute LV volume measurements. Methods Twenty patients with a recent myocardial infarction and good ultrasound image quality underwent 3DE using the TomTec Freehand method before and during continuous intravenous contrast infusion. LV volumes were measured offline using TomTec Echo-Scan software. Results The use of contrast enhancement increased end-diastolic (110±35 vs. 144±53 ml; p
ISSN:1568-5888
1876-6250
DOI:10.1007/BF03086117