Molecular relationship among Salmonella dublin isolates identified at the Center for Enterobacteriaceae of Palermo during the years 1971–85

A molecular epidemiological study was carried out on 60 Salmonella dublin isolates identified at the Southern Italy Enterobacteriaceae Center between 1971 and 1985. These included 23 isolates from children with diarrhoea in Palermo obtained during 1984. All isolates from the outbreak of gastroenteri...

Full description

Saved in:
Bibliographic Details
Published in:Epidemiology and infection 1987-10, Vol.99 (2), p.283-290
Main Authors: Nastasi, A., Villafrate, M. R., Mammina, C., Massenti, M. F., Oliva, D., Scarlata, G.
Format: Article
Language:English
Subjects:
Ampicillin Resistance
Animals
Antibiotic resistance
Antibiotics
Bacteriology
Biological and medical sciences
Cattle
Child
Children
Chloramphenicol Resistance
Disease Outbreaks
DNA, Bacterial - analysis
Drug Resistance, Microbial
Enterobacteriaceae
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Gastroenteritis - epidemiology
Gastroenteritis - microbiology
Humans
Infections
Italy
Metals - pharmacology
Mice
Mice, Inbred BALB C
Microbiology
Molecular weight
Plasmids
Salmonella
Salmonella - drug effects
Salmonella - genetics
Salmonella - pathogenicity
Salmonella Infections - epidemiology
Salmonella Infections - microbiology
Salmonella Infections, Animal - microbiology
Streptomycin - pharmacology
Tetracycline Resistance
Virulence
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A molecular epidemiological study was carried out on 60 Salmonella dublin isolates identified at the Southern Italy Enterobacteriaceae Center between 1971 and 1985. These included 23 isolates from children with diarrhoea in Palermo obtained during 1984. All isolates from the outbreak of gastroenteritis in children were resistant to chloramphenicol and streptomycin and harboured two plasmids of 50 MDa and 3 MDa molecular weight, whereas the majority of the isolates identified before 1984 were susceptible to these antibiotics and carried only a 50 MDa molecular weight plasmid. Four S. dublin strains successively identified from cattle (Palermo, Foggia, Portici) and from a child (Palermo) were shown to possess similar antibiotic resistance patterns and plasmid profiles to S. dublin isolates from the outbreak of gastroenteritis in children. The 50 MDa plasmid was shown to be associated with virulence in mice, while it was not possible to assign any genetic function to the 3 MDa plasmid.
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268800067753