Mammalian brainstem chemosensitive neurones: linking them to respiration in vitro

Neurones which are excited by CO 2 or H + are present in a number of brainstem structures in addition to the ventrolateral region of the medulla, the site at which the respiratory response to hypercapnia is traditionally believed to originate. In this review we examine recent work concerned with est...

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Bibliographic Details
Published in:The Journal of physiology 2000-06, Vol.525 (3), p.567-577
Main Authors: Ballantyne, D., Scheid, P.
Format: Article
Language:English
Subjects:
Animals
Chemoreceptor Cells - physiology
hypercapnia
Mammalia
Mammals
Medulla Oblongata - cytology
Medulla Oblongata - physiology
Neurons - physiology
Respiration
Respiratory Center - cytology
Respiratory Center - physiology
Topical Review
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Summary:Neurones which are excited by CO 2 or H + are present in a number of brainstem structures in addition to the ventrolateral region of the medulla, the site at which the respiratory response to hypercapnia is traditionally believed to originate. In this review we examine recent work concerned with establishing the relationship between these chemosensitive neurones and respiration, the emphasis being placed on the use for this purpose of in vitro preparations of the mammalian brainstem.
ISSN:0022-3751
1469-7793
DOI:10.1111/j.1469-7793.2000.00567.x