The development of an age structured model for schistosomiasis transmission dynamics and control and its validation for Schistosoma mansoni

Mathematical models are potentially useful tools to aid in the design of control programmes for parasitic diseases. In this paper, a fully age structured epidemiological model of human schistosomiasis is developed and parameterized, and used to predict trends in infection prevalence, intensity and p...

Full description

Saved in:
Bibliographic Details
Published in:Epidemiology and infection 1995-10, Vol.115 (2), p.325-344
Main Authors: Chan, M. S., Guyatt, H. L., Bundy, D. A. P., Booth, M., Fulford, A. J. C., Medley, G. F.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Age Distribution
Age Factors
Age groups
Aged
Biological and medical sciences
Child
Child, Preschool
Children
Diseases caused by trematodes
Eggs
Forecasting
Freshwater
Geometric mean
Helminthic diseases
Humans
Infant
Infections
Infectious diseases
Kenya - epidemiology
Medical sciences
Middle Aged
Modeling
Models, Statistical
Parametric models
Parasite Egg Count
Parasitic diseases
Population Surveillance
Predictive Value of Tests
Prevalence
Reproducibility of Results
Schistosoma mansoni
Schistosomiases
Schistosomiasis
Schistosomiasis mansoni - epidemiology
Schistosomiasis mansoni - parasitology
Schistosomiasis mansoni - prevention & control
Schistosomiasis mansoni - transmission
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Mathematical models are potentially useful tools to aid in the design of control programmes for parasitic diseases. In this paper, a fully age structured epidemiological model of human schistosomiasis is developed and parameterized, and used to predict trends in infection prevalence, intensity and prevalence of heavy infections over age and time during several rounds of mass and age targeted treatment. The model is validated against data from a Schistosoma mansoni control programme in Kenya.
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268800058453