Legionella pneumophila serogroup 1 population in Italy by monoclonal subtyping

The Oxford panel of monoclonal antibodies was used to subtype 83 strains of Legionella pneumophila serogroup 1 of human and environmental origin. The International panel was also used to subtype 50 of them. All the 18 patients' isolates were of the Pontiac subgroup, and 40/43 of the environment...

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Bibliographic Details
Published in:Epidemiology and infection 1990-08, Vol.105 (1), p.169-174
Main Authors: Pastoris, M. Castellani, McIntyre, M., Goldoni, P.
Format: Article
Language:English
Subjects:
Antibodies, Monoclonal
Antigens
Bacteriology
Biological and medical sciences
Disease outbreaks
Environmental disorders
Epidemiology
Fundamental and applied biological sciences. Psychology
Humans
Infections
Italy
Legionella
Legionella - classification
Legionella pneumophila
Legionnaires disease
Legionnaires' Disease - microbiology
Microbiology
Monoclonal antibodies
Serotyping
Special Article
Water supply
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Summary:The Oxford panel of monoclonal antibodies was used to subtype 83 strains of Legionella pneumophila serogroup 1 of human and environmental origin. The International panel was also used to subtype 50 of them. All the 18 patients' isolates were of the Pontiac subgroup, and 40/43 of the environmental strains of the Pontiac subgroup were associated with human infection. The remaining environmental strains were subgroups Olda (15 strains), Camperdown (5 strains), and Bellingham (2 strains). The Philadelphia subgroup was the commonest among the environmental strains tested with the international MABs panel. This study confirms previous findings that L. pneumophila serogroup 1 isolates with the Pontiac (Oxford panel) or MAB-2 (international panel) reacting antigen marker seem to be more virulent than the other subgroups.
ISSN:0950-2688
1469-4409
DOI:10.1017/S0950268800047750