An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data

Detection of differentially expressed genes from expressed sequence tags (ESTs) data has received much attention. An empirical Bayesian method is introduced in which gene expression patterns are estimated and used to define detection statistics. Significantly differentially expressed genes can be de...

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Bibliographic Details
Published in:International Journal of Plant Genomics 2008, Vol.2008 (2008), p.308-311
Main Authors: You, Na, Liu, Junmei, Mao, Chang Xuan
Format: Article
Language:English
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Summary:Detection of differentially expressed genes from expressed sequence tags (ESTs) data has received much attention. An empirical Bayesian method is introduced in which gene expression patterns are estimated and used to define detection statistics. Significantly differentially expressed genes can be declared given detection statistics. Simulation is done to evaluate the performance of proposed method. Two real applications are studied.
ISSN:1687-5370
1687-5389
DOI:10.1155/2008/817210