Central and peripheral mediation of human force sensation following eccentric or concentric contractions

• Published in: The Journal of physiology 2002-03, Vol.539 (3), p.913-925
• Main Authors: Carson, Richard G., Riek, Stephan, Shahbazpour, Nosratollah
• Format: Article
• Language: English
• Subjects: Adult; Arm; Biomarkers; Electric Stimulation; Electromyography; Evoked Potentials, Motor - physiology; Humans; Isometric Contraction - physiology; Magnetics; Male; Motor Cortex - physiology; Muscle Contraction - physiology; Muscle, Skeletal - metabolism; Muscle, Skeletal - pathology; Muscle, Skeletal - physiology; Original; Peripheral Nerves - physiology; Sensation - physiology
• ISSN: 0022-3751; 1469-7793
• DOI: 10.1113/jphysiol.2001.013385

Fatigue was induced in the triceps brachii of the experimental arm by a regimen of either eccentric or concentric muscle actions. Estimates of force were assessed using a contralateral limb-matching procedure, in which target force levels (25 %, 50 % or 75 % of maximum) were defined by the unfatigued control arm. Maximum isometric force-generating capacity was reduced by 31 % immediately following eccentric contractions, and remained depressed at 24 (25 %) and 48 h (13 %) post-exercise. A less marked reduction (8.3 %) was observed immediately following concentric contractions. Those participants who performed prior eccentric contractions, consistently (at all force levels), and persistently (throughout the recovery period), overestimated the level of force applied by the experimental arm. In other words, they believed that they were generating more force than they actually achieved. When the forces applied by the experimental and the control arm, were each expressed as a proportion of the maximum force that could be attained at that time, the estimates matched extremely closely. This outcome is that which would be expected if the estimates of force were based on a sense of effort. Following eccentric exercise, the amplitude of the EMG activity recorded from the experimental arm was substantially greater than that recorded from the control arm. Cortically evoked potentials recorded from the triceps brachii (and extensor carpi radialis) of the experimental arm were also substantially larger than those elicited prior to exercise. The sense of effort was evidently not based upon a corollary of the central motor command. Rather, the relationship between the sense of effort and the motor command appears to have been altered as a result of the fatiguing eccentric contractions. It is proposed that the sense of effort is associated with activity in neural centres upstream of the motor cortex.