Refining the role of laparoscopy and laparoscopic ultrasound in the staging of presumed pancreatic head and ampullary tumours

Laparoscopy and laparoscopic ultrasound have been validated previously as staging tools for pancreatic cancer. The aim of this study was to identify if assessment of vascular involvement with abdominal computed tomography (CT) would allow refinement of the selection criteria for laparoscopy and lapa...

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Bibliographic Details
Published in:British journal of cancer 2006-01, Vol.94 (2), p.213-217
Main Authors: Thomson, B N J, Parks, R W, Redhead, D N, Welsh, F K S, Madhavan, K K, Wigmore, S J, Garden, O J
Format: Article
Language:English
Subjects:
Abdomen
Adult
Aged
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Cancer Research
Clinical Study
Drug Resistance
Endosonography
Epidemiology
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Laparoscopy
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical imaging
Medical research
Medical sciences
Metastasis
Middle Aged
Molecular Medicine
Neoplasm Invasiveness - diagnosis
Neoplasm Staging
Oncology
Pancreatic cancer
Pancreatic Neoplasms - blood supply
Pancreatic Neoplasms - diagnostic imaging
Pancreatic Neoplasms - pathology
Patients
Tomography
Tomography, X-Ray Computed
Tumors
Ultrasonic imaging
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Description
Summary:Laparoscopy and laparoscopic ultrasound have been validated previously as staging tools for pancreatic cancer. The aim of this study was to identify if assessment of vascular involvement with abdominal computed tomography (CT) would allow refinement of the selection criteria for laparoscopy and laparoscopic ultrasound (LUS). The details of patients staged with LUS and abdominal CT were obtained from the unit's pancreatic cancer database. A CT grade (O, A-F) of vascular involvement was recorded by a single radiologist. Of 152 patients, who underwent a LUS, 56 (37%) had unresectable disease. Three of 26 (12%) patients with CT grade O, 27 of 88 (31%) patients with CT grade A to D, 17 of 29 (59%) patients with CT grade E and all nine patients with CT grade F were found to have unresectable disease. In all, 24% of patients with tumours
ISSN:0007-0920
1532-1827
DOI:10.1038/sj.bjc.6602919