Validation of a new prognostic index score for disseminated nasopharyngeal carcinoma

Patients with metastatic nasopharyngeal carcinoma have variable survival outcomes. We previously designed a scoring system to better prognosticate these patients. Here, we report results on validation of this new prognostic index score in a separate cohort of patients. Clinical features and laborato...

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Bibliographic Details
Published in:British journal of cancer 2005-04, Vol.92 (8), p.1382-1387
Main Authors: Toh, C-K, Heng, D, Ong, Y-K, Leong, S-S, Wee, J, Tan, E-H
Format: Article
Language:English
Subjects:
Antineoplastic Agents - therapeutic use
Biological and medical sciences
Biomedical and Life Sciences
Biomedicine
Cancer Research
Cancer therapies
Clinical Study
Drug Resistance
Epidemiology
Female
Hospitals
Humans
Male
Medical prognosis
Medical research
Medical sciences
Metastasis
Middle Aged
Molecular Medicine
Nasopharyngeal Neoplasms - classification
Nasopharyngeal Neoplasms - mortality
Nasopharyngeal Neoplasms - pathology
Neoplasm Metastasis - pathology
Oncology
Otorhinolaryngology. Stomatology
Prognosis
Risk Factors
Survival Analysis
Tumors
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Summary:Patients with metastatic nasopharyngeal carcinoma have variable survival outcomes. We previously designed a scoring system to better prognosticate these patients. Here, we report results on validation of this new prognostic index score in a separate cohort of patients. Clinical features and laboratory parameters were examined in 172 patients with univariate and multivariate analyses and a numerical score was derived for each independent prognostic variable. Significant independent prognostic variables and their scores assigned included poor performance status (score 5), haemoglobin
ISSN:0007-0920
1532-1827
DOI:10.1038/sj.bjc.6602525