System for prostate brachytherapy and biopsy in a standard 1.5 T MRI scanner

A technique for transperineal high‐dose‐rate (HDR) prostate brachytherapy and needle biopsy in a standard 1.5 T MRI scanner is demonstrated. In each of eight procedures (in four patients with intermediate to high risk localized prostate cancer), four MRI‐guided transperineal prostate biopsies were o...

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Bibliographic Details
Published in:Magnetic resonance in medicine 2004-09, Vol.52 (3), p.683-687
Main Authors: Susil, Robert C., Camphausen, Kevin, Choyke, Peter, McVeigh, Elliot R., Gustafson, Gary S., Ning, Holly, Miller, Robert W., Atalar, Ergin, Coleman, C. Norman, Ménard, Cynthia
Format: Article
Language:English
Subjects:
biopsy
Biopsy, Needle
brachytherapy
Brachytherapy - methods
Equipment Design
Humans
interventional MRI
Magnetic Resonance Imaging
Male
MRI
prostate
prostatic neoplasms
Prostatic Neoplasms - pathology
Prostatic Neoplasms - radiotherapy
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Summary:A technique for transperineal high‐dose‐rate (HDR) prostate brachytherapy and needle biopsy in a standard 1.5 T MRI scanner is demonstrated. In each of eight procedures (in four patients with intermediate to high risk localized prostate cancer), four MRI‐guided transperineal prostate biopsies were obtained followed by placement of 14–15 hollow transperineal catheters for HDR brachytherapy. Mean needle‐placement accuracy was 2.1 mm, 95% of needle‐placement errors were less than 4.0 mm, and the maximum needle‐placement error was 4.4 mm. In addition to guiding the placement of biopsy needles and brachytherapy catheters, MR images were also used for brachytherapy treatment planning and optimization. Because 1.5 T MR images are directly acquired during the interventional procedure, dependence on deformable registration is reduced and online image quality is maximized. Magn Reson Med 52:683–687, 2004. Published 2004 Wiley‐Liss, Inc.
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.20138