Use of amiodarone during pregnancy

Two cases are reported in which amiodarone was administered during pregnancy for longer periods than has been reported previously. Limited placental transfer of amiodarone and its desethyl metabolite was observed in both cases. A normal child resulted from each pregnancy despite, in one case, amioda...

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Bibliographic Details
Published in:Postgraduate medical journal 1985-01, Vol.61 (711), p.75-77
Main Authors: Robson, D. J., Jeeva Raj, M. V., Storey, G. C., Holt, D. W.
Format: Article
Language:English
Subjects:
Adult
Amiodarone - analogs & derivatives
Amiodarone - analysis
Amiodarone - therapeutic use
Arrhythmias, Cardiac - drug therapy
Benzofurans - therapeutic use
Female
Humans
Maternal-Fetal Exchange
Pregnancy
Pregnancy Complications, Cardiovascular - drug therapy
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Summary:Two cases are reported in which amiodarone was administered during pregnancy for longer periods than has been reported previously. Limited placental transfer of amiodarone and its desethyl metabolite was observed in both cases. A normal child resulted from each pregnancy despite, in one case, amiodarone therapy throughout the entire pregnancy. However, caution is urged in the use of amiodarone during pregnancy in view of the limited data available.
ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.61.711.75