Serological response to cholera revaccination in a semi-closed community in Calcutta

Serological response to cholera revaccination has been studied in a semi-closed community consisting of individuals mostly in the 2-20-years age-group. The subjects had been inoculated against cholera every year at the beginning of the local epidemic season. Pre- and post-vaccination sera were obtai...

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Bibliographic Details
Published in:Bulletin of the World Health Organization 1970, Vol.43 (3), p.407-412
Main Authors: Sinha, R, Deb, B C, Ganguly, R, De, S P, Abou-Gareeb, A H, Shrivastava, D L
Format: Article
Language:English
Subjects:
Adolescent
Agglutination Tests
Antibodies - analysis
Child
Child, Preschool
Cholera - immunology
Cholera Vaccines - therapeutic use
Humans
India
Vaccination
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Summary:Serological response to cholera revaccination has been studied in a semi-closed community consisting of individuals mostly in the 2-20-years age-group. The subjects had been inoculated against cholera every year at the beginning of the local epidemic season. Pre- and post-vaccination sera were obtained from 29 subjects inoculated with cholera vaccine (test group) and 28 from subjects inoculated with TAB vaccine (control group). These sera were tested for vibriocidal and agglutination titres. The geometrical means of the vibriocidal and agglutination titres of the post-vaccination sera in the test group rose by 490% and 463% respectively. This booster effect was observed mostly in individuals in the 2-14-years age-group, who had low titres (vibriocidal
ISSN:0042-9686