A report of acute overdosage of the anti-serotonergic drug pizotifen

An acute overdosage of 30 mg of pizotifen causing a pyrexial illness is reported. The clinical features suggest that the effects of overdosage are principally due to the anticholinergic activity of this drug. Resolution of symptoms occurred after 10 hours, without specific therapy.

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Bibliographic Details
Published in:Postgraduate medical journal 1987-01, Vol.63 (735), p.59-60
Main Authors: Griffiths, A. P., Penn, N. D., Tindall, H.
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Female
Fever - chemically induced
Humans
Pizotyline - poisoning
Thiophenes - poisoning
Online Access:Get full text
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Description
Summary:An acute overdosage of 30 mg of pizotifen causing a pyrexial illness is reported. The clinical features suggest that the effects of overdosage are principally due to the anticholinergic activity of this drug. Resolution of symptoms occurred after 10 hours, without specific therapy.
ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.63.735.59