Bilateral adrenal phaeochromocytomas associated with unilateral renal artery stenosis

A 21 year old male was discovered to be severely hypertensive. He was found to have bilateral adrenal phaeochromocytomas and a single renal artery stenosis. More than 40 cases of coexisting renal artery stenosis and phaeochromocytomas have been reported. The aetiology of renal artery stenosis in ass...

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Bibliographic Details
Published in:Postgraduate medical journal 1989-12, Vol.65 (770), p.943-947
Main Authors: Burns, A. P., O'Connell, P. R., Murnaghan, D. J., Brady, M. P.
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - blood
Adrenal Gland Neoplasms - complications
Adrenal Gland Neoplasms - diagnostic imaging
Adult
Angiography
Humans
Hypertension, Renovascular - etiology
Male
Pheochromocytoma - blood
Pheochromocytoma - complications
Pheochromocytoma - diagnostic imaging
Renal Artery Obstruction - blood
Renal Artery Obstruction - complications
Renal Artery Obstruction - diagnostic imaging
Renin - blood
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Summary:A 21 year old male was discovered to be severely hypertensive. He was found to have bilateral adrenal phaeochromocytomas and a single renal artery stenosis. More than 40 cases of coexisting renal artery stenosis and phaeochromocytomas have been reported. The aetiology of renal artery stenosis in association with phaeochromocytoma maybe multifactorial and the radiographic appearances are not always clear-cut. Renin levels in this patient were elevated prior to the removal of the phaeochromocytomas but the renal vein renin ratio did not suggest that the renal artery stenosis contributed significantly to his hypertension. The patient's hypertension resolved following successful removal of the phaeochromocytomas despite persistence of the renal artery stenosis. Thus, though renin levels may be misleading in these cases, renal vein renin ratios may still be helpful in deciding on patient management.
ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.65.770.943