Anaphylactic reactions to topical antibiotic combinations

We describe two patients who developed anaphylaxis type reactions following the application of the topical antibiotic Polyfax (polymixin B and bacitracin). We draw attention to this potentially serious complication of topical antibiotic preparations and emphasize the need for careful history taking...

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Bibliographic Details
Published in:Postgraduate medical journal 1990-10, Vol.66 (780), p.858-859
Main Authors: Eedy, D. J., McMillan, J. C., Bingham, E. A.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Anaphylaxis - chemically induced
Bacitracin - administration & dosage
Bacitracin - adverse effects
Drug Therapy, Combination - adverse effects
Female
Humans
Polymyxin B - administration & dosage
Polymyxin B - adverse effects
Varicose Ulcer - drug therapy
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Summary:We describe two patients who developed anaphylaxis type reactions following the application of the topical antibiotic Polyfax (polymixin B and bacitracin). We draw attention to this potentially serious complication of topical antibiotic preparations and emphasize the need for careful history taking before prescribing such preparations.
ISSN:0032-5473
1469-0756
DOI:10.1136/pgmj.66.780.858