Anaphylactic reactions to topical antibiotic combinations

We describe two patients who developed anaphylaxis type reactions following the application of the topical antibiotic Polyfax (polymixin B and bacitracin). We draw attention to this potentially serious complication of topical antibiotic preparations and emphasize the need for careful history taking...

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Published in:Postgraduate medical journal 1990-10, Vol.66 (780), p.858-859
Main Authors: Eedy, D. J., McMillan, J. C., Bingham, E. A.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Anaphylaxis - chemically induced
Bacitracin - administration & dosage
Bacitracin - adverse effects
Drug Therapy, Combination - adverse effects
Female
Humans
Polymyxin B - administration & dosage
Polymyxin B - adverse effects
Varicose Ulcer - drug therapy
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cited_by cdi_FETCH-LOGICAL-b489t-d40b9be8fa5c05127dfc39db58aa8951eb80cb0222e49c4f62c0652391dc8c23
cites cdi_FETCH-LOGICAL-b489t-d40b9be8fa5c05127dfc39db58aa8951eb80cb0222e49c4f62c0652391dc8c23
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container_title Postgraduate medical journal
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creator Eedy, D. J.
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description We describe two patients who developed anaphylaxis type reactions following the application of the topical antibiotic Polyfax (polymixin B and bacitracin). We draw attention to this potentially serious complication of topical antibiotic preparations and emphasize the need for careful history taking before prescribing such preparations.
doi_str_mv 10.1136/pgmj.66.780.858
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subjects Aged
Aged, 80 and over
Anaphylaxis - chemically induced
Bacitracin - administration & dosage
Bacitracin - adverse effects
Drug Therapy, Combination - adverse effects
Female
Humans
Polymyxin B - administration & dosage
Polymyxin B - adverse effects
Varicose Ulcer - drug therapy
title Anaphylactic reactions to topical antibiotic combinations
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