Transient Hemolytic Anemia after Transjugular Intrahepatic Portosystemic Stent Shunt

Management of variceal bleeding secondary to portal hypertension constitutes a challenging issue, particularly in child's C cirrhotic patients. Recently, transjugular placement of self-expanding metallic stents in the liver (TIPS), creating a shunt between the portal and hepatic branches has pr...

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Bibliographic Details
Published in:HPB Surgery 1996, Vol.1996 (4), p.249-251
Main Authors: SAGRARIO GARCIA-REBOLLO, EMILIO GONZÁLEZ-REIMERS, FRANCISCO SANTOLARIA-FERNÁNDEZ, FRANCISCO DIAZ-ROMERO, FERMIN RODRIGUEZ-MORENO, ANTONIO MARTINEZ-RIERA
Format: Article
Language:English
Subjects:
Aged
Anemia, Hemolytic - etiology
Humans
Liver Cirrhosis - surgery
Male
Portasystemic Shunt, Transjugular Intrahepatic - adverse effects
Reoperation
Stents - adverse effects
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Summary:Management of variceal bleeding secondary to portal hypertension constitutes a challenging issue, particularly in child's C cirrhotic patients. Recently, transjugular placement of self-expanding metallic stents in the liver (TIPS), creating a shunt between the portal and hepatic branches has provided a safe and promising therapeutic approach in this clinical situation. We report here the case of a 66-year-old male cirrhotic patient who developed a moderately severe clinical picture of a Coombsnegative hemolytic anemia (serum hemoglobin, 93 g/l, serum bilirubin 160.74 umol/L (9.4 mg/dl), indirect 6.3 mg/dl (107.73 umol/L); serum LDH 1220 u/l, reticulocytes, 5.1%. serum ferritin, 1221 ug/1, schistocytes in peripheral blood smear) the week after undergoing a TIPS, suggesting the development of a microangiopathic hemolytic anaemia secondary to red blood cell disruption by passing through the metallic network of the stent.
ISSN:0894-8569
1607-8462
DOI:10.1155/1996/19343