Depression as an independent determinant of decreased heart rate variability in patients post myocardial infarction

Depression is associated with an increased risk of cardiac morbidity and mortality in patients following myocardial infarction (MI). Our objective was to investigate the potential role of the autonomic nervous system in mediating this detrimental effect. The study group consisted of 95 consecutive p...

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Bibliographic Details
Published in:Netherlands heart journal 2005-05, Vol.13 (5), p.165-169
Main Authors: van den Berg, M P, Spijkerman, T A, van Melle, J P, van den Brink, R H S, Winter, J B, Veeger, N J, Ormel, J
Format: Article
Language:English
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Summary:Depression is associated with an increased risk of cardiac morbidity and mortality in patients following myocardial infarction (MI). Our objective was to investigate the potential role of the autonomic nervous system in mediating this detrimental effect. The study group consisted of 95 consecutive post-MI patients without depression and 53 post-MI patients with depression. Depressive symptoms were assessed by the Beck Depression Inventory (BDI). Activity of the autonomic nervous system was assessed by analysing heart rate variability (HRV) using 24-hour ambulatory electrocardiographic recordings as obtained three months post MI. Higher age, female gender and left ventricular ejection fraction
ISSN:1568-5888