Anti-Toxoplasma gondii Antibodies in Patients With Schizophrenia-Preliminary Findings in a Turkish Sample

Schizophrenia is a serious neuropsychiatric disease of uncertain etiology. We investigated the seropositivity rate for anti-Toxoplasma IgG and IgM antibodies by enzyme-linked immunosorbent assay (ELISA) in patients with schizophrenia to ascertain a possible relationship between Toxoplasma gondii and...

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Bibliographic Details
Published in:Schizophrenia bulletin 2007-05, Vol.33 (3), p.789-791
Main Authors: Cetinkaya, Zafer, Yazar, Suleyman, Gecici, Omer, Namli, Mustafa N.
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Animals
Antibodies, Protozoan - blood
Biological and medical sciences
Comorbidity
Cross-Sectional Studies
Depressive Disorder - diagnosis
Depressive Disorder - epidemiology
Depressive Disorder - immunology
Enzyme-Linked Immunosorbent Assay
Female
Humans
Immunoglobulin G - blood
Immunoglobulin M - blood
Male
Medical sciences
Middle Aged
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Regular
Schizophrenia
Schizophrenia - diagnosis
Schizophrenia - epidemiology
Schizophrenia - immunology
Statistics as Topic
Toxoplasma - immunology
Toxoplasmosis, Cerebral - diagnosis
Toxoplasmosis, Cerebral - epidemiology
Toxoplasmosis, Cerebral - immunology
Turkey
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Summary:Schizophrenia is a serious neuropsychiatric disease of uncertain etiology. We investigated the seropositivity rate for anti-Toxoplasma IgG and IgM antibodies by enzyme-linked immunosorbent assay (ELISA) in patients with schizophrenia to ascertain a possible relationship between Toxoplasma gondii and schizophrenia. We selected 100 patients with schizophrenia, 50 with depressive disorder, and 50 healthy volunteers to investigate the seropositivity rate of anti-Toxoplasma antibodies by ELISA. The seropositivity rate for anti-Toxoplasma IgG antibodies among schizophrenia patients (66%) was significantly higher than among patients with depressive disorder or healthy volunteers (P 
ISSN:0586-7614
1745-1701
DOI:10.1093/schbul/sbm021