The routinisation of genomics and genetics: implications for ethical practices

Among bioethicists and members of the public, genetics is often regarded as unique in its ethical challenges. As medical researchers and clinicians increasingly combine genetic information with a range of non-genetic information in the study and clinical management of patients with common diseases,...

Full description

Saved in:
Bibliographic Details
Published in:Journal of medical ethics 2006-11, Vol.32 (11), p.635-638
Main Authors: Foster, M W, Royal, C D M, Sharp, R R
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
AIDS
Analysis
Attitude to Health
Bioethical Issues
Bioethics
Clinical ethics
Culture
Diabetes
Ethics
Forecasts and trends
Genetic Determinism
Genetic diseases
Genetic Privacy
Genetic research
Genetic Research - ethics
Genetics
Genetics, Medical - ethics
Genomics
Genomics - ethics
Heart diseases
HIV
Human genetics
Human immunodeficiency virus
Humans
institutional review board
IRB
Market trend/market analysis
Medical ethics
Medical genetics
Medical research
Public Opinion
Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-b583t-f05454897d1b3e950ea5d4ebf120f60077a01cffb1a5653489d02cf2243f075a3
cites cdi_FETCH-LOGICAL-b583t-f05454897d1b3e950ea5d4ebf120f60077a01cffb1a5653489d02cf2243f075a3
container_end_page 638
container_issue 11
container_start_page 635
container_title Journal of medical ethics
container_volume 32
creator Foster, M W
Royal, C D M
Sharp, R R
description Among bioethicists and members of the public, genetics is often regarded as unique in its ethical challenges. As medical researchers and clinicians increasingly combine genetic information with a range of non-genetic information in the study and clinical management of patients with common diseases, the unique ethical challenges attributed to genetics must be re-examined. A process of genetic routinisation that will have implications for research and clinical ethics, as well as for public conceptions of genetic information, is constituted by the emergence of new forms of genetic medicine, in which genetic information is interpreted in a multifactorial frame of reference. Although the integration of genetics in medical research and treatment may be a helpful corrective to the mistaken assumptions of genetic essentialism or determinism, the routinisation of genetics may have unintended consequences for the protection of genetic information, perceptions of non-genetic information and the loss of genetic research as a laboratory for exploring issues in research and clinical ethics. Consequently, new ethical challenges are presented by the increasing routinisation of genetic information in both biomedical and public spheres.
doi_str_mv 10.1136/jme.2005.013532
format article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2563298</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A155404713</galeid><jstor_id>27719741</jstor_id><sourcerecordid>A155404713</sourcerecordid><originalsourceid>FETCH-LOGICAL-b583t-f05454897d1b3e950ea5d4ebf120f60077a01cffb1a5653489d02cf2243f075a3</originalsourceid><addsrcrecordid>eNqFks2L1DAYxoMo7rh69qQUBA9CZ98kTdN6ENbBLxh2Ecb1GNI2mUltkzFJRf97M3aYVS-bS3h5fu9H3jwIPcWwxJiWF_2olgSALQFTRsk9tMAFp3lBGL-PFkChzMsK4Aw9CqGHdEhVP0RnmAMvKgILdLXZqcy7KRprgozG2czpbKusG00bMmm7Q6BiCl5nZtwPpv1DhUw7n6m4S_GQ7b1sE6LCY_RAyyGoJ8f7HH15_26z-pivrz98Wl2u84ZVNOYaWMGKquYdbqiqGSjJukI1GhPQJQDnEnCrdYMlKxlNZAek1YQUVANnkp6jN3Pd_dSMqmuVjV4OYu_NKP0v4aQR_yrW7MTW_RCElZTUVSrw8ljAu--TClGMJrRqGKRVbgqirAFXgOFOkEDFKAOawBf_gb2bvE1bEJhXGBjHlCcqn6mtHJQwtnU2qp-xdcOgtkqkJa2uxSVmrIAiJST-YuZb70LwSp_eiEEcLCCSBcTBAmK2QMp4_vdqbvnjnyfg2Qz0ITp_0gnnuOYFvh3RhDTaSZf-myg55Uxc3azE1_Xn8mbD3opDw1cz34z9ndP9BmHi0Vc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1781057137</pqid></control><display><type>article</type><title>The routinisation of genomics and genetics: implications for ethical practices</title><source>Open Access: PubMed Central</source><source>JSTOR Archival Journals and Primary Sources Collection</source><source>Social Science Premium Collection (Proquest) (PQ_SDU_P3)</source><source>Art, Design &amp; Architecture Collection</source><creator>Foster, M W ; Royal, C D M ; Sharp, R R</creator><creatorcontrib>Foster, M W ; Royal, C D M ; Sharp, R R</creatorcontrib><description>Among bioethicists and members of the public, genetics is often regarded as unique in its ethical challenges. As medical researchers and clinicians increasingly combine genetic information with a range of non-genetic information in the study and clinical management of patients with common diseases, the unique ethical challenges attributed to genetics must be re-examined. A process of genetic routinisation that will have implications for research and clinical ethics, as well as for public conceptions of genetic information, is constituted by the emergence of new forms of genetic medicine, in which genetic information is interpreted in a multifactorial frame of reference. Although the integration of genetics in medical research and treatment may be a helpful corrective to the mistaken assumptions of genetic essentialism or determinism, the routinisation of genetics may have unintended consequences for the protection of genetic information, perceptions of non-genetic information and the loss of genetic research as a laboratory for exploring issues in research and clinical ethics. Consequently, new ethical challenges are presented by the increasing routinisation of genetic information in both biomedical and public spheres.</description><identifier>ISSN: 0306-6800</identifier><identifier>EISSN: 1473-4257</identifier><identifier>DOI: 10.1136/jme.2005.013532</identifier><identifier>PMID: 17074820</identifier><identifier>CODEN: JMETDR</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and Institute of Medical Ethics</publisher><subject>Acquired immune deficiency syndrome ; AIDS ; Analysis ; Attitude to Health ; Bioethical Issues ; Bioethics ; Clinical ethics ; Culture ; Diabetes ; Ethics ; Forecasts and trends ; Genetic Determinism ; Genetic diseases ; Genetic Privacy ; Genetic research ; Genetic Research - ethics ; Genetics ; Genetics, Medical - ethics ; Genomics ; Genomics - ethics ; Heart diseases ; HIV ; Human genetics ; Human immunodeficiency virus ; Humans ; institutional review board ; IRB ; Market trend/market analysis ; Medical ethics ; Medical genetics ; Medical research ; Public Opinion ; Studies</subject><ispartof>Journal of medical ethics, 2006-11, Vol.32 (11), p.635-638</ispartof><rights>Copyright 2006 by the Journal of Medical Ethics</rights><rights>Copyright 2006 BMJ Publishing Group Ltd &amp; Institute of Medical Ethics</rights><rights>Copyright: 2006 Copyright 2006 by the Journal of Medical Ethics</rights><rights>Copyright ©2006 BMJ Publishing Group Ltd &amp; Institute of Medical Ethics.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b583t-f05454897d1b3e950ea5d4ebf120f60077a01cffb1a5653489d02cf2243f075a3</citedby><cites>FETCH-LOGICAL-b583t-f05454897d1b3e950ea5d4ebf120f60077a01cffb1a5653489d02cf2243f075a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1781057137/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1781057137?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,12861,21394,27924,27925,33611,33612,34775,34776,43733,44200,53791,53793,58238,58471,74221,74728</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17074820$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Foster, M W</creatorcontrib><creatorcontrib>Royal, C D M</creatorcontrib><creatorcontrib>Sharp, R R</creatorcontrib><title>The routinisation of genomics and genetics: implications for ethical practices</title><title>Journal of medical ethics</title><addtitle>J Med Ethics</addtitle><description>Among bioethicists and members of the public, genetics is often regarded as unique in its ethical challenges. As medical researchers and clinicians increasingly combine genetic information with a range of non-genetic information in the study and clinical management of patients with common diseases, the unique ethical challenges attributed to genetics must be re-examined. A process of genetic routinisation that will have implications for research and clinical ethics, as well as for public conceptions of genetic information, is constituted by the emergence of new forms of genetic medicine, in which genetic information is interpreted in a multifactorial frame of reference. Although the integration of genetics in medical research and treatment may be a helpful corrective to the mistaken assumptions of genetic essentialism or determinism, the routinisation of genetics may have unintended consequences for the protection of genetic information, perceptions of non-genetic information and the loss of genetic research as a laboratory for exploring issues in research and clinical ethics. Consequently, new ethical challenges are presented by the increasing routinisation of genetic information in both biomedical and public spheres.</description><subject>Acquired immune deficiency syndrome</subject><subject>AIDS</subject><subject>Analysis</subject><subject>Attitude to Health</subject><subject>Bioethical Issues</subject><subject>Bioethics</subject><subject>Clinical ethics</subject><subject>Culture</subject><subject>Diabetes</subject><subject>Ethics</subject><subject>Forecasts and trends</subject><subject>Genetic Determinism</subject><subject>Genetic diseases</subject><subject>Genetic Privacy</subject><subject>Genetic research</subject><subject>Genetic Research - ethics</subject><subject>Genetics</subject><subject>Genetics, Medical - ethics</subject><subject>Genomics</subject><subject>Genomics - ethics</subject><subject>Heart diseases</subject><subject>HIV</subject><subject>Human genetics</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>institutional review board</subject><subject>IRB</subject><subject>Market trend/market analysis</subject><subject>Medical ethics</subject><subject>Medical genetics</subject><subject>Medical research</subject><subject>Public Opinion</subject><subject>Studies</subject><issn>0306-6800</issn><issn>1473-4257</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>ALSLI</sourceid><sourceid>K50</sourceid><sourceid>M1D</sourceid><sourceid>M2R</sourceid><recordid>eNqFks2L1DAYxoMo7rh69qQUBA9CZ98kTdN6ENbBLxh2Ecb1GNI2mUltkzFJRf97M3aYVS-bS3h5fu9H3jwIPcWwxJiWF_2olgSALQFTRsk9tMAFp3lBGL-PFkChzMsK4Aw9CqGHdEhVP0RnmAMvKgILdLXZqcy7KRprgozG2czpbKusG00bMmm7Q6BiCl5nZtwPpv1DhUw7n6m4S_GQ7b1sE6LCY_RAyyGoJ8f7HH15_26z-pivrz98Wl2u84ZVNOYaWMGKquYdbqiqGSjJukI1GhPQJQDnEnCrdYMlKxlNZAek1YQUVANnkp6jN3Pd_dSMqmuVjV4OYu_NKP0v4aQR_yrW7MTW_RCElZTUVSrw8ljAu--TClGMJrRqGKRVbgqirAFXgOFOkEDFKAOawBf_gb2bvE1bEJhXGBjHlCcqn6mtHJQwtnU2qp-xdcOgtkqkJa2uxSVmrIAiJST-YuZb70LwSp_eiEEcLCCSBcTBAmK2QMp4_vdqbvnjnyfg2Qz0ITp_0gnnuOYFvh3RhDTaSZf-myg55Uxc3azE1_Xn8mbD3opDw1cz34z9ndP9BmHi0Vc</recordid><startdate>200611</startdate><enddate>200611</enddate><creator>Foster, M W</creator><creator>Royal, C D M</creator><creator>Sharp, R R</creator><general>BMJ Publishing Group Ltd and Institute of Medical Ethics</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Group</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>88J</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>AABKS</scope><scope>ABSDQ</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AVQMV</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K50</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1D</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>M2R</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200611</creationdate><title>The routinisation of genomics and genetics: implications for ethical practices</title><author>Foster, M W ; Royal, C D M ; Sharp, R R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b583t-f05454897d1b3e950ea5d4ebf120f60077a01cffb1a5653489d02cf2243f075a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Acquired immune deficiency syndrome</topic><topic>AIDS</topic><topic>Analysis</topic><topic>Attitude to Health</topic><topic>Bioethical Issues</topic><topic>Bioethics</topic><topic>Clinical ethics</topic><topic>Culture</topic><topic>Diabetes</topic><topic>Ethics</topic><topic>Forecasts and trends</topic><topic>Genetic Determinism</topic><topic>Genetic diseases</topic><topic>Genetic Privacy</topic><topic>Genetic research</topic><topic>Genetic Research - ethics</topic><topic>Genetics</topic><topic>Genetics, Medical - ethics</topic><topic>Genomics</topic><topic>Genomics - ethics</topic><topic>Heart diseases</topic><topic>HIV</topic><topic>Human genetics</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>institutional review board</topic><topic>IRB</topic><topic>Market trend/market analysis</topic><topic>Medical ethics</topic><topic>Medical genetics</topic><topic>Medical research</topic><topic>Public Opinion</topic><topic>Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Foster, M W</creatorcontrib><creatorcontrib>Royal, C D M</creatorcontrib><creatorcontrib>Sharp, R R</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection【Remote access available】</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Philosophy Collection</collection><collection>Philosophy Database</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>Arts Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Art, Design &amp; Architecture Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Arts &amp; Humanities Database</collection><collection>Medical Database</collection><collection>ProQuest research library</collection><collection>Science Database</collection><collection>Social Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of medical ethics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Foster, M W</au><au>Royal, C D M</au><au>Sharp, R R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The routinisation of genomics and genetics: implications for ethical practices</atitle><jtitle>Journal of medical ethics</jtitle><addtitle>J Med Ethics</addtitle><date>2006-11</date><risdate>2006</risdate><volume>32</volume><issue>11</issue><spage>635</spage><epage>638</epage><pages>635-638</pages><issn>0306-6800</issn><eissn>1473-4257</eissn><coden>JMETDR</coden><abstract>Among bioethicists and members of the public, genetics is often regarded as unique in its ethical challenges. As medical researchers and clinicians increasingly combine genetic information with a range of non-genetic information in the study and clinical management of patients with common diseases, the unique ethical challenges attributed to genetics must be re-examined. A process of genetic routinisation that will have implications for research and clinical ethics, as well as for public conceptions of genetic information, is constituted by the emergence of new forms of genetic medicine, in which genetic information is interpreted in a multifactorial frame of reference. Although the integration of genetics in medical research and treatment may be a helpful corrective to the mistaken assumptions of genetic essentialism or determinism, the routinisation of genetics may have unintended consequences for the protection of genetic information, perceptions of non-genetic information and the loss of genetic research as a laboratory for exploring issues in research and clinical ethics. Consequently, new ethical challenges are presented by the increasing routinisation of genetic information in both biomedical and public spheres.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and Institute of Medical Ethics</pub><pmid>17074820</pmid><doi>10.1136/jme.2005.013532</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0306-6800
ispartof Journal of medical ethics, 2006-11, Vol.32 (11), p.635-638
issn 0306-6800
1473-4257
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2563298
source Open Access: PubMed Central; JSTOR Archival Journals and Primary Sources Collection; Social Science Premium Collection (Proquest) (PQ_SDU_P3); Art, Design & Architecture Collection
subjects Acquired immune deficiency syndrome
AIDS
Analysis
Attitude to Health
Bioethical Issues
Bioethics
Clinical ethics
Culture
Diabetes
Ethics
Forecasts and trends
Genetic Determinism
Genetic diseases
Genetic Privacy
Genetic research
Genetic Research - ethics
Genetics
Genetics, Medical - ethics
Genomics
Genomics - ethics
Heart diseases
HIV
Human genetics
Human immunodeficiency virus
Humans
institutional review board
IRB
Market trend/market analysis
Medical ethics
Medical genetics
Medical research
Public Opinion
Studies
title The routinisation of genomics and genetics: implications for ethical practices
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T06%3A40%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20routinisation%20of%20genomics%20and%20genetics:%20implications%20for%20ethical%20practices&rft.jtitle=Journal%20of%20medical%20ethics&rft.au=Foster,%20M%20W&rft.date=2006-11&rft.volume=32&rft.issue=11&rft.spage=635&rft.epage=638&rft.pages=635-638&rft.issn=0306-6800&rft.eissn=1473-4257&rft.coden=JMETDR&rft_id=info:doi/10.1136/jme.2005.013532&rft_dat=%3Cgale_pubme%3EA155404713%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-b583t-f05454897d1b3e950ea5d4ebf120f60077a01cffb1a5653489d02cf2243f075a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1781057137&rft_id=info:pmid/17074820&rft_galeid=A155404713&rft_jstor_id=27719741&rfr_iscdi=true