Prevalence of IgA and IgG antichlamydial antibodies in women in the third trimester of pregnancy

The prevalence of serum antichlamydial IgA and IgG antibodies was investigated by screening 77 randomly selected patients who were in the third trimester of pregnancy. An indirect immunoperoxidase assay that quantitates IgA and IgG was used for screening. Twenty-five women had both IgA and IgG antib...

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Bibliographic Details
Published in:Journal of the National Medical Association 1988-11, Vol.80 (11), p.1201-1203
Main Authors: Osborne, N G, Hecht, Y, Gorsline, J, Forbes, B A, Morgenstern, F, Winkelman, J
Format: Article
Language:English
Subjects:
Chlamydia Infections - immunology
Chlamydia trachomatis - immunology
Female
Humans
Immunoglobulin A - analysis
Immunoglobulin G - analysis
Original Communications
Pregnancy
Pregnancy Complications, Infectious - immunology
Pregnancy Trimester, Third
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Summary:The prevalence of serum antichlamydial IgA and IgG antibodies was investigated by screening 77 randomly selected patients who were in the third trimester of pregnancy. An indirect immunoperoxidase assay that quantitates IgA and IgG was used for screening. Twenty-five women had both IgA and IgG antibodies; an additional ten women had only IgG antibodies. These findings suggest that greater than 45 percent of pregnant women tested had been exposed to Chlamydia trachomatis, and more than 32 percent had evidence of active infection.
ISSN:0027-9684