Image Reconstruction for a Partially Collimated Whole Body PET Scanner

Partially collimated PET systems have less collimation than conventional 2-D systems and have been shown to offer count rate improvements over 2-D and 3-D systems. Despite this potential, previous efforts have not established image-based improvements with partial collimation and have not customized...

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Bibliographic Details
Published in:IEEE transactions on nuclear science 2008-06, Vol.55 (3), p.975-983
Main Authors: Alessio, Adam M., Schmitz, Ruth E., MacDonald, Lawrence R., Wollenweber, Scott D., Stearns, Charles W., Ross, Steven G., Ganin, Alex, Lewellen, Thomas K., Kinahan, Paul E.
Format: Article
Language:English
Subjects:
2.5D
Brain modeling
Collimation
Collimators
Counting
Detectors
fully 3-D PET
Image quality
Image reconstruction
Medical services
National electric code
normalization
Polyethylene terephthalates
Positron emission tomography
Reconstruction
Reconstruction algorithms
Scatter
scatter estimation
Scattering
septa
Simulation
Whole-body PET
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Summary:Partially collimated PET systems have less collimation than conventional 2-D systems and have been shown to offer count rate improvements over 2-D and 3-D systems. Despite this potential, previous efforts have not established image-based improvements with partial collimation and have not customized the reconstruction method for partially collimated data. This work presents an image reconstruction method tailored for partially collimated data. Simulated and measured sensitivity patterns are presented and provide a basis for modification of a fully 3-D reconstruction technique. The proposed method uses a measured normalization correction term to account for the unique sensitivity to true events. This work also proposes a modified scatter correction based on simulated data. Measured image quality data supports the use of the normalization correction term for true events, and suggests that the modified scatter correction is unnecessary.
ISSN:0018-9499
1558-1578
DOI:10.1109/TNS.2008.921938