Loading…

A chromatic explosion: the development and future of multiparameter flow cytometry

Summary Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry a...

Full description

Saved in:
Bibliographic Details
Published in:Immunology 2008-12, Vol.125 (4), p.441-449
Main Authors: Chattopadhyay, Pratip K., Hogerkorp, Carl‐Magnus, Roederer, Mario
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c5039-6c6e8c1a7470d25f55d320438d5c81f8e55efa9e0aa35750ec854c541a51aa4f3
cites cdi_FETCH-LOGICAL-c5039-6c6e8c1a7470d25f55d320438d5c81f8e55efa9e0aa35750ec854c541a51aa4f3
container_end_page 449
container_issue 4
container_start_page 441
container_title Immunology
container_volume 125
creator Chattopadhyay, Pratip K.
Hogerkorp, Carl‐Magnus
Roederer, Mario
description Summary Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry and discuss future advances in the field. Finally, we highlight new applications that use this technology to reveal previously unappreciated aspects of cell biology and immunity.
doi_str_mv 10.1111/j.1365-2567.2008.02989.x
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2612557</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>19559500</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5039-6c6e8c1a7470d25f55d320438d5c81f8e55efa9e0aa35750ec854c541a51aa4f3</originalsourceid><addsrcrecordid>eNqNkU1v1DAQhi0EokvhLyCfuCX4I5PYSCBVVYFKrZAQnC3jjNmsnDjYSbv770nYVYET-GKP5plXYz2EUM5KvpzXu5LLGgoBdVMKxlTJhFa63D8im4fGY7JhjOtCKAZn5FnOu6WUDOApOeOay6aumg35fEHdNsXeTp2juB9DzF0c3tBpi7TFOwxx7HGYqB1a6udpTkijp_0cpm60yfY4YaI-xHvqDlNcynR4Tp54GzK-ON3n5Ov7qy-XH4ubTx-uLy9uCgdM6qJ2NSrHbVM1rBXgAVopWCVVC05xrxAAvdXIrJXQAEOnoHJQcQvc2srLc_LumDvO33ps3bJmssGMqettOphoO_N3Z-i25nu8M6LmAqBZAl6dAlL8MWOeTN9lhyHYAeOcTa211CCqf4JcA2hgbAHVEXQp5pzQP2zDmVnNmZ1ZBZlVkFnNmV_mzH4Zffnnb34PnlQtwNsjcN8FPPx3sLm-vV1f8idip6mZ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19559500</pqid></control><display><type>article</type><title>A chromatic explosion: the development and future of multiparameter flow cytometry</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><source>PubMed Central</source><creator>Chattopadhyay, Pratip K. ; Hogerkorp, Carl‐Magnus ; Roederer, Mario</creator><creatorcontrib>Chattopadhyay, Pratip K. ; Hogerkorp, Carl‐Magnus ; Roederer, Mario</creatorcontrib><description>Summary Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry and discuss future advances in the field. Finally, we highlight new applications that use this technology to reveal previously unappreciated aspects of cell biology and immunity.</description><identifier>ISSN: 0019-2805</identifier><identifier>EISSN: 1365-2567</identifier><identifier>DOI: 10.1111/j.1365-2567.2008.02989.x</identifier><identifier>PMID: 19137647</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Animals ; Coloring Agents ; data analysis ; Equipment Design ; flow cytometry ; Flow Cytometry - methods ; Flow Cytometry - trends ; fluorochromes ; Forecasting ; Humans ; Immune System Diseases - diagnosis ; Review ; Statistics as Topic ; T cells ; tetramers</subject><ispartof>Immunology, 2008-12, Vol.125 (4), p.441-449</ispartof><rights>2008 Blackwell Publishing Ltd. No claim to original US government works</rights><rights>2008 Blackwell Publishing Ltd 2008</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5039-6c6e8c1a7470d25f55d320438d5c81f8e55efa9e0aa35750ec854c541a51aa4f3</citedby><cites>FETCH-LOGICAL-c5039-6c6e8c1a7470d25f55d320438d5c81f8e55efa9e0aa35750ec854c541a51aa4f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612557/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612557/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19137647$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chattopadhyay, Pratip K.</creatorcontrib><creatorcontrib>Hogerkorp, Carl‐Magnus</creatorcontrib><creatorcontrib>Roederer, Mario</creatorcontrib><title>A chromatic explosion: the development and future of multiparameter flow cytometry</title><title>Immunology</title><addtitle>Immunology</addtitle><description>Summary Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry and discuss future advances in the field. Finally, we highlight new applications that use this technology to reveal previously unappreciated aspects of cell biology and immunity.</description><subject>Animals</subject><subject>Coloring Agents</subject><subject>data analysis</subject><subject>Equipment Design</subject><subject>flow cytometry</subject><subject>Flow Cytometry - methods</subject><subject>Flow Cytometry - trends</subject><subject>fluorochromes</subject><subject>Forecasting</subject><subject>Humans</subject><subject>Immune System Diseases - diagnosis</subject><subject>Review</subject><subject>Statistics as Topic</subject><subject>T cells</subject><subject>tetramers</subject><issn>0019-2805</issn><issn>1365-2567</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNqNkU1v1DAQhi0EokvhLyCfuCX4I5PYSCBVVYFKrZAQnC3jjNmsnDjYSbv770nYVYET-GKP5plXYz2EUM5KvpzXu5LLGgoBdVMKxlTJhFa63D8im4fGY7JhjOtCKAZn5FnOu6WUDOApOeOay6aumg35fEHdNsXeTp2juB9DzF0c3tBpi7TFOwxx7HGYqB1a6udpTkijp_0cpm60yfY4YaI-xHvqDlNcynR4Tp54GzK-ON3n5Ov7qy-XH4ubTx-uLy9uCgdM6qJ2NSrHbVM1rBXgAVopWCVVC05xrxAAvdXIrJXQAEOnoHJQcQvc2srLc_LumDvO33ps3bJmssGMqettOphoO_N3Z-i25nu8M6LmAqBZAl6dAlL8MWOeTN9lhyHYAeOcTa211CCqf4JcA2hgbAHVEXQp5pzQP2zDmVnNmZ1ZBZlVkFnNmV_mzH4Zffnnb34PnlQtwNsjcN8FPPx3sLm-vV1f8idip6mZ</recordid><startdate>200812</startdate><enddate>200812</enddate><creator>Chattopadhyay, Pratip K.</creator><creator>Hogerkorp, Carl‐Magnus</creator><creator>Roederer, Mario</creator><general>Blackwell Publishing Ltd</general><general>Blackwell Science Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>200812</creationdate><title>A chromatic explosion: the development and future of multiparameter flow cytometry</title><author>Chattopadhyay, Pratip K. ; Hogerkorp, Carl‐Magnus ; Roederer, Mario</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5039-6c6e8c1a7470d25f55d320438d5c81f8e55efa9e0aa35750ec854c541a51aa4f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>Coloring Agents</topic><topic>data analysis</topic><topic>Equipment Design</topic><topic>flow cytometry</topic><topic>Flow Cytometry - methods</topic><topic>Flow Cytometry - trends</topic><topic>fluorochromes</topic><topic>Forecasting</topic><topic>Humans</topic><topic>Immune System Diseases - diagnosis</topic><topic>Review</topic><topic>Statistics as Topic</topic><topic>T cells</topic><topic>tetramers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chattopadhyay, Pratip K.</creatorcontrib><creatorcontrib>Hogerkorp, Carl‐Magnus</creatorcontrib><creatorcontrib>Roederer, Mario</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chattopadhyay, Pratip K.</au><au>Hogerkorp, Carl‐Magnus</au><au>Roederer, Mario</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A chromatic explosion: the development and future of multiparameter flow cytometry</atitle><jtitle>Immunology</jtitle><addtitle>Immunology</addtitle><date>2008-12</date><risdate>2008</risdate><volume>125</volume><issue>4</issue><spage>441</spage><epage>449</epage><pages>441-449</pages><issn>0019-2805</issn><eissn>1365-2567</eissn><abstract>Summary Multiparameter flow cytometry has matured tremendously since the 1990s, giving rise to a technology that allows us to study the immune system in unprecedented detail. In this article, we review the development of hardware, reagents, and data analysis tools for multiparameter flow cytometry and discuss future advances in the field. Finally, we highlight new applications that use this technology to reveal previously unappreciated aspects of cell biology and immunity.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19137647</pmid><doi>10.1111/j.1365-2567.2008.02989.x</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0019-2805
ispartof Immunology, 2008-12, Vol.125 (4), p.441-449
issn 0019-2805
1365-2567
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2612557
source Wiley-Blackwell Read & Publish Collection; PubMed Central
subjects Animals
Coloring Agents
data analysis
Equipment Design
flow cytometry
Flow Cytometry - methods
Flow Cytometry - trends
fluorochromes
Forecasting
Humans
Immune System Diseases - diagnosis
Review
Statistics as Topic
T cells
tetramers
title A chromatic explosion: the development and future of multiparameter flow cytometry
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T23%3A19%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20chromatic%20explosion:%20the%20development%20and%20future%20of%20multiparameter%20flow%20cytometry&rft.jtitle=Immunology&rft.au=Chattopadhyay,%20Pratip%20K.&rft.date=2008-12&rft.volume=125&rft.issue=4&rft.spage=441&rft.epage=449&rft.pages=441-449&rft.issn=0019-2805&rft.eissn=1365-2567&rft_id=info:doi/10.1111/j.1365-2567.2008.02989.x&rft_dat=%3Cproquest_pubme%3E19559500%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5039-6c6e8c1a7470d25f55d320438d5c81f8e55efa9e0aa35750ec854c541a51aa4f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=19559500&rft_id=info:pmid/19137647&rfr_iscdi=true