Intrahepatic extramedullary hematopoiesis mimicking a hypervascular hepatic neoplasm on dynamic- and SPIO-enhanced MRI

We present a rare case of a focal intrahepatic extramedullary hematopoiesis (EMH) that mimicked a hypervascular hepatic neoplasm in a 33-year-old woman with idiopathic myelofibrosis. The lesion showed homogeneous and persistent enhancement on both contrast-enhanced CT and gadolinium-enhanced dynamic...

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Bibliographic Details
Published in:Korean journal of radiology 2008-07, Vol.9 Suppl (Suppl), p.S34-S38
Main Authors: Lee, In Joon, Kim, Se Hyung, Kim, Dae Sik, Lee, Jeong Min, Han, Joon Koo, Choi, Byung Ihn
Format: Article
Language:English
Subjects:
Adenoma - diagnosis
Adult
Bone marrow
Case Report
Case reports
Contrast agents
Diagnosis, Differential
Disease
Hematology
Hematopoiesis, Extramedullary
Humans
Liver - physiology
Liver cancer
Liver Neoplasms - diagnosis
Magnetic Resonance Imaging
Male
Primary Myelofibrosis - physiopathology
Spleen
Tumors
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Summary:We present a rare case of a focal intrahepatic extramedullary hematopoiesis (EMH) that mimicked a hypervascular hepatic neoplasm in a 33-year-old woman with idiopathic myelofibrosis. The lesion showed homogeneous and persistent enhancement on both contrast-enhanced CT and gadolinium-enhanced dynamic MR imaging. The lesion did not demonstrate an apparent signal drop on a T2-weighted sequence following administration of a superparamagnetic iron-oxide agent (SHU 555A). A hepatocellular adenoma was the initial radiological diagnosis. To the best of our knowledge, this is the first report of a histopathologically proven intrahepatic EMH evaluated with dynamic- and SPIO-enhanced MRI.
ISSN:1229-6929
2005-8330
DOI:10.3348/kjr.2008.9.s.s34