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In addition to traditional T and N staging, patients were stratified into ‘limited regional’ disease (node-negative T1, T2) and ‘advanced regional’ disease (T3N0 and any N1 disease).The accuracy of EUS in identifying patients who would benefit from neoadjuvant therapy based on the above criteria was...

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Bibliographic Details
Published in:Annals of the Royal College of Surgeons of England 2008-09, Vol.90 (6), p.527-528
Format: Article
Language:English
Subjects:
Cancer therapies
Chemotherapy
Colorectal cancer
Electrolytes
Metastasis
Trainees' Presentations
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Summary:In addition to traditional T and N staging, patients were stratified into ‘limited regional’ disease (node-negative T1, T2) and ‘advanced regional’ disease (T3N0 and any N1 disease).The accuracy of EUS in identifying patients who would benefit from neoadjuvant therapy based on the above criteria was determined. The sensitivity of EUS for predicting the above group of patients who would benefit from neoadjuvant chemotherapy was 83% with a positive predictive value of 89%. EUS is a valuable tool to identify this subset of patients in whom neoadjuvant chemotherapy offers a survival benefit following surgery.
ISSN:0035-8843
1478-7083
DOI:10.1308/003588408X321549