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Frailty and Mortality Among Chinese at Advanced Ages

Objectives This study investigates the factors associated with frailty and the association of frailty with mortality in a national sample of adults aged 65-109 in China. Methods Using the 2002 wave of the Chinese Longitudinal Healthy Longevity Survey, we construct a frailty index (FI) based on 39 me...

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Published in:The journals of gerontology. Series B, Psychological sciences and social sciences Psychological sciences and social sciences, 2009-03, Vol.64B (2), p.279-289
Main Authors: Gu, Danan, Dupre, Matthew E., Sautter, Jessica, Zhu, Haiyan, Liu, Yuzhi, Yi, Zeng
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container_title The journals of gerontology. Series B, Psychological sciences and social sciences
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creator Gu, Danan
Dupre, Matthew E.
Sautter, Jessica
Zhu, Haiyan
Liu, Yuzhi
Yi, Zeng
description Objectives This study investigates the factors associated with frailty and the association of frailty with mortality in a national sample of adults aged 65-109 in China. Methods Using the 2002 wave of the Chinese Longitudinal Healthy Longevity Survey, we construct a frailty index (FI) based on 39 measures available in the data set. We use ordinal logistic regressions to examine the factors associated with the FI and use Weibull hazard regression to examine the association between frailty and 3-year mortality from 2002 to 2005. Results Age, sex, ethnicity, urban-rural residence, economic condition, religious involvement, and daily exercise are significantly associated with levels of frailty. Hazard analyses further reveal that the FI is a robust predictor of mortality at advanced ages and that the relationship between frailty and mortality is independent of various covariates. Discussion The measurement and analysis of frailty have broad implications for public health initiatives designed to target individuals with the diminished capacity to effectively compensate for external stressors and to prevent further declines associated with aging and mortality. A key to healthy longevity is the prevention, postponement, and potential recovery from physical and cognitive deficits at advanced ages through enhanced medical interventions and treatments.
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Methods Using the 2002 wave of the Chinese Longitudinal Healthy Longevity Survey, we construct a frailty index (FI) based on 39 measures available in the data set. We use ordinal logistic regressions to examine the factors associated with the FI and use Weibull hazard regression to examine the association between frailty and 3-year mortality from 2002 to 2005. Results Age, sex, ethnicity, urban-rural residence, economic condition, religious involvement, and daily exercise are significantly associated with levels of frailty. Hazard analyses further reveal that the FI is a robust predictor of mortality at advanced ages and that the relationship between frailty and mortality is independent of various covariates. Discussion The measurement and analysis of frailty have broad implications for public health initiatives designed to target individuals with the diminished capacity to effectively compensate for external stressors and to prevent further declines associated with aging and mortality. A key to healthy longevity is the prevention, postponement, and potential recovery from physical and cognitive deficits at advanced ages through enhanced medical interventions and treatments.</description><identifier>ISSN: 1079-5014</identifier><identifier>EISSN: 1758-5368</identifier><identifier>DOI: 10.1093/geronb/gbn009</identifier><identifier>PMID: 19196691</identifier><identifier>CODEN: JGBSF3</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Activities of Daily Living - classification ; Age ; Aged ; Aged, 80 and over ; Aging ; China ; Chronic Disease - ethnology ; Chronic Disease - mortality ; Data collection ; Developing Countries ; Disability Evaluation ; Economic Conditions ; Ethnicity ; Female ; Frail Elderly - statistics &amp; numerical data ; Frailty ; Hazards ; Health care ; Health initiatives ; Health Policy ; Humans ; Industrialized nations ; Intervention ; Journal of Gerontology: Social Sciences ; LDCs ; Longevity ; Longitudinal Studies ; Male ; Mortality ; Mortality Rates ; Older people ; Peoples Republic of China ; Postponement ; Prevention ; Proportional Hazards Models ; Risk ; Risk factors ; Sex Factors ; Social Environment ; Social Support ; Socioeconomic Factors ; Stress ; Studies ; Survival Analysis</subject><ispartof>The journals of gerontology. 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Hazard analyses further reveal that the FI is a robust predictor of mortality at advanced ages and that the relationship between frailty and mortality is independent of various covariates. Discussion The measurement and analysis of frailty have broad implications for public health initiatives designed to target individuals with the diminished capacity to effectively compensate for external stressors and to prevent further declines associated with aging and mortality. 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Series B, Psychological sciences and social sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gu, Danan</au><au>Dupre, Matthew E.</au><au>Sautter, Jessica</au><au>Zhu, Haiyan</au><au>Liu, Yuzhi</au><au>Yi, Zeng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Frailty and Mortality Among Chinese at Advanced Ages</atitle><jtitle>The journals of gerontology. Series B, Psychological sciences and social sciences</jtitle><addtitle>J Gerontol B Psychol Sci Soc Sci</addtitle><date>2009-03-01</date><risdate>2009</risdate><volume>64B</volume><issue>2</issue><spage>279</spage><epage>289</epage><pages>279-289</pages><issn>1079-5014</issn><eissn>1758-5368</eissn><coden>JGBSF3</coden><abstract>Objectives This study investigates the factors associated with frailty and the association of frailty with mortality in a national sample of adults aged 65-109 in China. Methods Using the 2002 wave of the Chinese Longitudinal Healthy Longevity Survey, we construct a frailty index (FI) based on 39 measures available in the data set. We use ordinal logistic regressions to examine the factors associated with the FI and use Weibull hazard regression to examine the association between frailty and 3-year mortality from 2002 to 2005. Results Age, sex, ethnicity, urban-rural residence, economic condition, religious involvement, and daily exercise are significantly associated with levels of frailty. Hazard analyses further reveal that the FI is a robust predictor of mortality at advanced ages and that the relationship between frailty and mortality is independent of various covariates. Discussion The measurement and analysis of frailty have broad implications for public health initiatives designed to target individuals with the diminished capacity to effectively compensate for external stressors and to prevent further declines associated with aging and mortality. A key to healthy longevity is the prevention, postponement, and potential recovery from physical and cognitive deficits at advanced ages through enhanced medical interventions and treatments.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>19196691</pmid><doi>10.1093/geronb/gbn009</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record>
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identifier ISSN: 1079-5014
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source Applied Social Sciences Index & Abstracts (ASSIA); Oxford Journals Online; Sociological Abstracts
subjects Activities of Daily Living - classification
Age
Aged
Aged, 80 and over
Aging
China
Chronic Disease - ethnology
Chronic Disease - mortality
Data collection
Developing Countries
Disability Evaluation
Economic Conditions
Ethnicity
Female
Frail Elderly - statistics & numerical data
Frailty
Hazards
Health care
Health initiatives
Health Policy
Humans
Industrialized nations
Intervention
Journal of Gerontology: Social Sciences
LDCs
Longevity
Longitudinal Studies
Male
Mortality
Mortality Rates
Older people
Peoples Republic of China
Postponement
Prevention
Proportional Hazards Models
Risk
Risk factors
Sex Factors
Social Environment
Social Support
Socioeconomic Factors
Stress
Studies
Survival Analysis
title Frailty and Mortality Among Chinese at Advanced Ages
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