Homotyrosine-Containing Cyanopeptolins 880 and 960 and Anabaenopeptins 908 and 915 from Planktothrix agardhii CYA 126/8

Two homotyrosine-bearing cyanopeptolins are described from Planktothrix agardhii CYA 126/8. The compounds feature a common homotyrosine-containing cyclohexadepsipeptide and differ by sulfation of an exocyclically located 2-O-methyl- d -glyceric acid residue. In addition we describe two anabaenopepti...

Full description

Saved in:
Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2009-01, Vol.72 (1), p.172-176
Main Authors: Okumura, Hilary S, Philmus, Benjamin, Portmann, Cyril, Hemscheidt, Thomas K
Format: Article
Language:English
Subjects:
anabaenopeptin
Bacteriology
Biological and medical sciences
chemical structure
Cyanobacteria - chemistry
cyanopeptolin
cyclic peptides
cyclohexadepsipeptide
Depsipeptides
Fundamental and applied biological sciences. Psychology
Hawaii
Microbiology
microcystins
Molecular Structure
Morphology, structure, chemical composition
Nuclear Magnetic Resonance, Biomolecular
Peptides, Cyclic - chemistry
Peptides, Cyclic - isolation & purification
Planktothrix agardhii
spectral analysis
tyrosine
Tyrosine - analogs & derivatives
Tyrosine - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Two homotyrosine-bearing cyanopeptolins are described from Planktothrix agardhii CYA 126/8. The compounds feature a common homotyrosine-containing cyclohexadepsipeptide and differ by sulfation of an exocyclically located 2-O-methyl- d -glyceric acid residue. In addition we describe two anabaenopeptins, which contain two homotyrosine residues, one of which is N-methylated. The anabaenopeptins have a common cyclopentapeptide portion and differ in the amino acid linked to it via an ureido bond, arginine and tyrosine, respectively.
ISSN:0163-3864
1520-6025
DOI:10.1021/np800557m