Lack of effect of subject posture on intravenous midazolam clearance: implications for hepatic cytochrome P450 3A phenotyping

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Bibliographic Details
Published in:British journal of clinical pharmacology 2009-03, Vol.67 (3), p.374-375
Main Authors: Ma, Joseph D., Nafziger, Anne N., Mylott, William, Haughey, David B., Rocci Jr, Mario L., Bertino Jr, Joseph S.
Format: Article
Language:English
Subjects:
Cytochrome P-450 CYP3A - drug effects
Female
Humans
Injections, Intravenous
Letter to the Editors
Liver - blood supply
Liver - drug effects
Male
Metabolic Clearance Rate - drug effects
Midazolam - blood
Midazolam - pharmacokinetics
Posture - physiology
Regional Blood Flow - drug effects
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ISSN:0306-5251
1365-2125
DOI:10.1111/j.1365-2125.2008.03361.x