Metabolic Syndrome and Ischemic Stroke Risk : Northern Manhattan Study

More than 47 million individuals in the United States meet the criteria for the metabolic syndrome. The relation between the metabolic syndrome and stroke risk in multiethnic populations has not been well characterized. As part of the Northern Manhattan Study, 3298 stroke-free community residents we...

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Published in:Stroke (1970) 2008-01, Vol.39 (1), p.30-35
Main Authors: BODEN-ALBALA, Bernadette, SACCO, Ralph L, PAIK, Myunghee C, LEE, Hye-Sueng, GRAHAME-CLARKE, Cairistine, RUNDEK, Tanja, ELKIND, Mitchell V, WRIGHT, Clinton, GIARDINA, Elsa-Grace V, DITULLIO, Marco R, HOMMA, Shunichi
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Biological and medical sciences
Black or African American
Black People - ethnology
Blood. Blood coagulation. Reticuloendothelial system
Cohort Studies
Female
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Hispanic or Latino - ethnology
Humans
Kaplan-Meier Estimate
Male
Medical sciences
Metabolic Syndrome - epidemiology
Metabolic Syndrome - ethnology
Middle Aged
Nervous system (semeiology, syndromes)
Neurology
New York City - epidemiology
Pharmacology. Drug treatments
Prevalence
Prospective Studies
Risk Factors
Sex Characteristics
Stroke - epidemiology
Stroke - ethnology
Vascular diseases and vascular malformations of the nervous system
White People - ethnology
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Summary:More than 47 million individuals in the United States meet the criteria for the metabolic syndrome. The relation between the metabolic syndrome and stroke risk in multiethnic populations has not been well characterized. As part of the Northern Manhattan Study, 3298 stroke-free community residents were prospectively followed up for a mean of 6.4 years. The metabolic syndrome was defined according to guidelines established by the National Cholesterol Education Program Adult Treatment Panel III. Cox proportional-hazards models were used to calculate hazard ratios (HRs) and 95% CIs for ischemic stroke and vascular events (ischemic stroke, myocardial infarction, or vascular death). The etiologic fraction estimates the proportion of events attributable to the metabolic syndrome. More than 44% of the cohort had the metabolic syndrome (48% of women vs 38% of men, P
ISSN:0039-2499
1524-4628
1524-4628
DOI:10.1161/STROKEAHA.107.496588