Transforming Environmental Health Protection

We propose a shift from primarily in vivo animal studies to in vitro assays, in vivo assays with lower organisms, and computational modeling for toxicity assessments.

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2008-02, Vol.319 (5865), p.906-907
Main Authors: Collins, Francis S., Gray, George M., Bucher, John R.
Format: Article
Language:English
Subjects:
Animal models
Animals
Cell lines
Chemical hazards
Dose response relationship
Drug design
Environmental agencies
Humans
Liver
Policy Forum
Toxicology
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Description
Summary:We propose a shift from primarily in vivo animal studies to in vitro assays, in vivo assays with lower organisms, and computational modeling for toxicity assessments.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1154619