Epigenetic transmission of piRNAs through the female germline

In Drosophila, small RNAs bound to Piwi proteins are epigenetic factors transmitted from the mother to the progeny germline. This ensures 'immunization' of progeny against transposable elements.

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Bibliographic Details
Published in:Genome biology 2009-02, Vol.10 (2), p.208-208
Main Authors: Shpiz, Sergey, Kalmykova, Alla
Format: Article
Language:English
Subjects:
Animals
Argonaute Proteins
DNA Transposable Elements
Drosophila - genetics
Drosophila Proteins - genetics
Epigenesis, Genetic - genetics
Female
Genomic Imprinting
Germ Cells
Minireview
RNA, Small Interfering - genetics
RNA-Induced Silencing Complex - genetics
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Description
Summary:In Drosophila, small RNAs bound to Piwi proteins are epigenetic factors transmitted from the mother to the progeny germline. This ensures 'immunization' of progeny against transposable elements.
ISSN:1465-6906
1474-760X
1465-6914
DOI:10.1186/gb-2009-10-2-208