Primary lymphoblastic B-cell lymphoma of the stomach: a case report

Primary stomach lymphoblastic B-cell lymphoma (B-LBL) is a rare tumor. We describe a primary stomach B-LBL in a 38 years old female who presented with nonspecific complaints of fatigue and vomiting for 2 mo. Gastrofiberscopy revealed a large gastric ulcer, which was successfully resected. Pathology...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2008-05, Vol.14 (19), p.3101-3104
Main Authors: He, Miao-Xia, Zhu, Ming-Hua, Liu, Wei-Qiang, Wu, Li-Li, Zhu, Xiong-Zeng
Format: Article
Language:English
Subjects:
Adult
Case Report
Female
Fiber Optic Technology
Gastroscopy - methods
Gene Expression Regulation, Neoplastic
Gene Rearrangement, B-Lymphocyte
Humans
Immunohistochemistry
Immunophenotyping
Lymphoma, B-Cell - genetics
Lymphoma, B-Cell - immunology
Lymphoma, B-Cell - pathology
Lymphoma, B-Cell - surgery
Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology
Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology
Precursor Cell Lymphoblastic Leukemia-Lymphoma - surgery
Stomach Neoplasms - genetics
Stomach Neoplasms - immunology
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Stomach Ulcer - pathology
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Summary:Primary stomach lymphoblastic B-cell lymphoma (B-LBL) is a rare tumor. We describe a primary stomach B-LBL in a 38 years old female who presented with nonspecific complaints of fatigue and vomiting for 2 mo. Gastrofiberscopy revealed a large gastric ulcer, which was successfully resected. Pathology showed a lymphoblastic cell lymphoma arising from the stomach, and there was no evidence of disease at any extrastomach site. Immunohistochemical staining and gene rearrangement studies supported that the stomach tumor was a clonal B-cell lymphoma. Therefore, the diagnosis of B-LBL was made based on the stomach specimen.
ISSN:1007-9327
DOI:10.3748/wjg.14.3101