Relationship between metabolic syndrome and familial history of hypertension/stroke, diabetes, and cardiovascular disease

• Published in: Journal of Korean medical science 2006-08, Vol.21 (4), p.701-708
• Main Authors: Paek, Kyung Won, Chun, Ki Hong, Lee, Kwan Woo
• Format: Article
• Language: English
• Subjects: Adult; Age Distribution; Age Factors; Aged; Cardiovascular Diseases - genetics; Diabetes Mellitus - genetics; Family Health; Female; Genetic Predisposition to Disease - genetics; Humans; Hypertension - genetics; Korea - epidemiology; Male; Metabolic Syndrome - epidemiology; Metabolic Syndrome - genetics; Middle Aged; Odds Ratio; Original; Prevalence; Sex Factors; Stroke - genetics
• ISSN: 1011-8934; 1598-6357
• DOI: 10.3346/jkms.2006.21.4.701

This research analyzes the prevalence of metabolic syndrome (MS) in Korea and examines how the presence of a familial history of diseases related to MS, such as hypertension/stroke, cardiovascular disease, and diabetes, affect the development of MS in Koreans. The prevalence of MS and its components, as defined by the Nation-al Cholesterol Education Program Adult Treatment Panel guidelines, were evaluated in nationally representative samples of non-institutionalized civilian Koreans. This analysis is based on the 2001 Korea National Health and Nutrition Examination Survey, which used a stratified multistage probability sampling design. The final study included 5,742 adults who had completed the necessary health examinations and met the diagnosis of MS. The prevalence of MS was 25.5% in men and 28.7% in women. Odds ratio for MS among men with a familial history of hypertension/stroke was higher than that among men who did not have this history. The OR for MS among women with a familial history of hypertension/stroke or diabetes was higher than that among women who had no familial history of these diseases. These results show that familial history of hypertension/stroke and diabetes was significantly related to the presence of MS in both young men and women.