Perfusion CT evaluation in experimentally induced testicular torsion

In this study, we define the characteristics of perfusion computed tomography (CT) in an experimental model of testicular torsion. Twenty male Sprague-Dawley rats were included for the study. Torsion was applied to 10 rats and perfusion CT was performed in the first hour to evaluate the following pe...

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Bibliographic Details
Published in:Canadian Urological Association journal 2009-10, Vol.3 (5), p.383-386
Main Authors: Ovali, Gulgun Yilmaz, Yilmaz, Omer, Tarhan, Serdar, Genc, Abdulkadir, Demireli, Peyker, Tunçyurek, Ozum, Unden, Cansu, Taneli, Can, Pabuscu, Yüksel
Format: Article
Language:English
Subjects:
Animal models in research
Care and treatment
CT imaging
Diagnosis
Health aspects
Original Research
Spermatic cord torsion
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Summary:In this study, we define the characteristics of perfusion computed tomography (CT) in an experimental model of testicular torsion. Twenty male Sprague-Dawley rats were included for the study. Torsion was applied to 10 rats and perfusion CT was performed in the first hour to evaluate the following perfusion parameters: blood flow (BF), blood volume (BV) and time to peak (TTP) values. Detorsion was done for the same rats, and perfusion CT was repeated 2 hours later to evaluate reperfusion. Ten rats were left as part of the control group. There is significant statistical correlation between the BF and BV values in the torsion and control groups (p = 0.001 and p = 0.001, respectively). There is no statistical correlation of the TTP parameters between the groups. No correlation was found between torsion and detorsion perfusion parameters. Perfusion CT can demonstrate the testicular perfusion insult in an experimental model of torsion. Perfusion CT may be an alternative method for diagnosis of torsion in indeterminate cases. Following detorsion an interval of 2 hours is not sufficient for demonstrating luxury perfusion of the testis.
ISSN:1911-6470
1920-1214