Clinical outcomes of patients with KPC-producing Klebsiella pneumoniae following treatment with imipenem or meropenem

KPC-producing Klebsiella pneumoniae may appear susceptible to imipenem or meropenem by routine susceptibility testing. We report a series of patients with infectious caused by K. pneumoniae isolates that yielded imipenem-susceptible results but were subsequently KPC-positive by PCR. When these infec...

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Bibliographic Details
Published in:Diagnostic microbiology and infectious disease 2009-04, Vol.64 (2), p.233-235
Main Authors: Weisenberg, Scott A., Morgan, Daniel J., Espinal-Witter, Rosanny, Larone, Davise H.
Format: Article
Language:English
Online Access:Get full text
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Summary:KPC-producing Klebsiella pneumoniae may appear susceptible to imipenem or meropenem by routine susceptibility testing. We report a series of patients with infectious caused by K. pneumoniae isolates that yielded imipenem-susceptible results but were subsequently KPC-positive by PCR. When these infections were treated with imipenem or meropenem, frequent clinical and microbiological failures were observed.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2009.02.004