Relationship of Prospective Memory to Neuropsychological Function and Antiretroviral Adherence

Prospective memory is defined as the ability to “remember to remember” something at a future time despite intervening distractions and may be particularly important in remembering to take prescribed medication among people infected with HIV. Ninety-seven HIV-positive participants in a clinical trial...

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Bibliographic Details
Published in:Archives of clinical neuropsychology 2009-09, Vol.24 (6), p.547-554
Main Authors: Contardo, Christopher, Black, Anne C., Beauvais, John, Dieckhaus, Kevin, Rosen, Marc I.
Format: Article
Language:English
Subjects:
Adherence
Adult
Adult and adolescent clinical studies
Aged
Anti-Retroviral Agents - therapeutic use
Biological and medical sciences
Cognition Disorders - complications
Cognition Disorders - psychology
Female
HIV
HIV Seropositivity - complications
HIV Seropositivity - drug therapy
Human immunodeficiency virus
Human viral diseases
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infectious diseases
Male
Medical sciences
Medication Adherence - psychology
Medication compliance
Memory
Middle Aged
Neuropsychological function
Neuropsychological Tests
Organic mental disorders. Neuropsychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Research Papers
Substance use
Substance-Related Disorders - complications
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Prospective memory is defined as the ability to “remember to remember” something at a future time despite intervening distractions and may be particularly important in remembering to take prescribed medication among people infected with HIV. Ninety-seven HIV-positive participants in a clinical trial had their adherence measured by electronic pillcaps and were administered neuropsychological screening tests and the memory for intentions screening test (MIST). Factor analysis of the MIST and other neuropsychological measures identified four factors. Two were derived from MIST subscales and accounted for approximately 50% of the variance in cognitive functioning. Only one factor was significantly correlated with adherence, and this was a MIST factor. In this preliminary study, the MIST assessed a memory function that (a) could be distinguished from traditional retrospective recall and executive functioning and (b) was correlated with antiretroviral adherence.
ISSN:0887-6177
1873-5843
DOI:10.1093/arclin/acp046