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Spatial Patterns in Discordant Diagnostic Test Results for Chagas Disease: Links to Transmission Hotspots
Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. In periurban Arequipa, Peru, spatial analysis revealed that individuals with discordant test results are spatially clustered in hotspots of T. cruzi transmission, s...
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Published in: | Clinical infectious diseases 2009-04, Vol.48 (8), p.1104-1106 |
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creator | Levy, Michael Z. Bowman, Natalie M. Kawai, Vivian Plotkin, Joshua B. Waller, Lance A. Cabrera, Lilia Steurer, Frank Seitz, Amy E. Cancino, Viviana V. Pinedo Cornejo del Carpio, Juan Geny Benzaquen, Eleazar Cordova McKenzie, F. Ellis Maguire, James H. Gilman, Robert H. Bern, Caryn |
description | Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. In periurban Arequipa, Peru, spatial analysis revealed that individuals with discordant test results are spatially clustered in hotspots of T. cruzi transmission, suggesting that discordant results likely represent true infections in this setting. |
doi_str_mv | 10.1086/597464 |
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Pinedo</creatorcontrib><creatorcontrib>Cornejo del Carpio, Juan Geny</creatorcontrib><creatorcontrib>Benzaquen, Eleazar Cordova</creatorcontrib><creatorcontrib>McKenzie, F. Ellis</creatorcontrib><creatorcontrib>Maguire, James H.</creatorcontrib><creatorcontrib>Gilman, Robert H.</creatorcontrib><creatorcontrib>Bern, Caryn</creatorcontrib><title>Spatial Patterns in Discordant Diagnostic Test Results for Chagas Disease: Links to Transmission Hotspots</title><title>Clinical infectious diseases</title><addtitle>Clinical Infectious Diseases</addtitle><addtitle>Clinical Infectious Diseases</addtitle><description>Diagnosis of Chagas disease is hindered by discordance between screening and confirmatory test results for Trypanosoma cruzi infection. 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source | JSTOR Archival Journals and Primary Sources Collection; Oxford Journals Online |
subjects | Animals Biological and medical sciences Brief Reports Chagas disease Chagas Disease - diagnosis Chagas Disease - epidemiology Chagas Disease - transmission Children Cluster Analysis Communities Computer Simulation Disease transmission Enzyme-Linked Immunosorbent Assay Fluorescent Antibody Technique Human protozoal diseases Humans Infections Infectious diseases Medical diagnosis Medical diagnostic tests Medical sciences Medical screening Models, Biological Monte Carlo Method Null hypothesis Parasitic diseases Peru - epidemiology Protozoal diseases Radioimmunoprecipitation Assay Screening tests Statistics Time Factors Topography, Medical Trypanosoma cruzi Trypanosoma cruzi - isolation & purification Trypanosomiasis |
title | Spatial Patterns in Discordant Diagnostic Test Results for Chagas Disease: Links to Transmission Hotspots |
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