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P16-11. HLA-B57/5801 induces preferential CD27 expression on HIV-Gag but not Nef specific central memory CD8+T cells controlling HIV

To gain novel insight into the nature of the protective effect mediated by HIV-specific CD8+T cells in HLA-B57/5801+ individuals, we compared the frequency, cytokine production, differentiation, and functional avidity of HIV-specific CD8+T cells in B57/5801+ and B57/5801- nonprogressors.

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Bibliographic Details
Published in:Retrovirology 2009-10, Vol.6 (Suppl 3), p.P240-P240, Article P240
Main Authors: Xie, J, Lu, W, Samri, A, Costagliola, D, Schnuriger, A, da Silva, BC, Blanc, C, Almeida, M, Pellé, O, Theodorou, I, Rouzioux, C, Autran, B
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Language:English
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Summary:To gain novel insight into the nature of the protective effect mediated by HIV-specific CD8+T cells in HLA-B57/5801+ individuals, we compared the frequency, cytokine production, differentiation, and functional avidity of HIV-specific CD8+T cells in B57/5801+ and B57/5801- nonprogressors.
ISSN:1742-4690
1742-4690
DOI:10.1186/1742-4690-6-S3-P240