A Cognitive Map for Object Memory in the Hippocampus

The hippocampus has been proposed to support a cognitive map, a mental representation of the spatial layout of an environment as well as the nonspatial items encountered in that environment. In the present study, we recorded simultaneously from 43 to 61 hippocampal pyramidal cells as rats performed...

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Bibliographic Details
Published in:Learning & memory (Cold Spring Harbor, N.Y.) N.Y.), 2009-10, Vol.16 (10), p.616-624
Main Authors: Manns, Joseph R, Eichenbaum, Howard
Format: Article
Language:English
Subjects:
Animals
Brain Hemisphere Functions
Brain Mapping
Cognitive Mapping
Cytology
Electrophysiology
Hippocampus - physiology
Infants
Male
Memory
Memory - physiology
Multivariate Analysis
Pyramidal Cells - physiology
Rats
Rats, Long-Evans
Recognition (Psychology)
Task Analysis
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Summary:The hippocampus has been proposed to support a cognitive map, a mental representation of the spatial layout of an environment as well as the nonspatial items encountered in that environment. In the present study, we recorded simultaneously from 43 to 61 hippocampal pyramidal cells as rats performed an object recognition memory task in which novel and repeated objects were encountered in different locations on a circular track. Multivariate analyses of the neural data indicated that information about object identity was represented secondarily to the primary information dimension of object location. In addition, the neural data related to performance on the recognition memory task. The results suggested that objects were represented as points of interest on the hippocampal cognitive map and that this map was useful in remembering encounters with particular objects in specific locations.
ISSN:1072-0502
1549-5485
DOI:10.1101/lm.1484509